Evidence map›Paper›PMID 30700748›Full record

ArticleScientific reports2019

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Claudia M Tellez Freitas, Haley R Burrell, Jonard C Valdoz, Garrett J Hamblin, Carlee M Raymond, Tyler D Cox, Deborah K Johnson, Joshua L Andersen, K Scott Weber, Laura C Bridgewater

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Claudia M Tellez FreitasDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.ORCID 0000-0002-9218-3021
Haley R BurrellDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.
Jonard C ValdozDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, United States of America.ORCID 0000-0002-7106-1009
Garrett J HamblinDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.
Carlee M RaymondDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.
Tyler D CoxDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.
Deborah K JohnsonDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.ORCID 0000-0002-4575-9841
Joshua L AndersenDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, United States of America.
K Scott WeberDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America.ORCID 0000-0003-3688-2191
Laura C BridgewaterDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, United States of America. laura_bridgewater@byu.edu.ORCID 0000-0002-4664-6144
Brigham Young University · US

Funding

The role of antigenic strength in the primary and memory responses of pathogen spR15AI107753 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI WEBER, K. SCOTT · 2013 to 2013
$449k
NIAID NIH HHS R15 AI107753U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R15CA202619U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R0102063
6 · The paper itself

Abstract

We previously identified a nuclear variant of bone morphogenetic protein 2 (BMP2), named nBMP2, that is translated from an alternative start codon. Decreased nuclear localization of nBMP2 in the nBmp2NLS

Indexed as

Gene ExpressionAnimalsBone Morphogenetic Protein 2CalciumCell NucleusMacrophagesMiceMice, TransgenicNuclear ProteinsStaphylococcal InfectionsStaphylococcus aureusBmp2 protein, mouseBone Morphogenetic Protein 2CalciumNuclear Proteins

Identifiers

PMID30700748
PMCPMC6353957
OpenAlexW2921392577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.