ArticleNature communications2019
Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05649436 (Assessment of Developmental Status and Locomotor Balance in Healthy Children. A Normative Study.), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Developmental Status and Locomotor Balance in Healthy Children. A Normative Study.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heavy metals and neurodevelopment of children in low and middle-income countries: A systematic review.PloS one · 2022Pooled it
- Normative growth trajectories of fetal brain regions validated by satisfactory maturation of neurodevelopmental domains at 2 years of age.Nature communications · 2026Article
- Sleep and infant development in the first year.Pediatric research · 2026Article
- Recent challenges in children's developmental milestones.Pediatric research · 2025Article
- NorthPop: a prospective population-based birth cohort study.BMC public health · 2025Article
- Using machine learning to investigate the influence of the prenatal chemical exposome on neurodevelopment of young children.Neurotoxicology · 2025Article
- Association between twin status with cognitive, behavioral development and brain structure in early adolescence: a retrospective cohort analysis based on the Adolescent Brain Cognitive Development Study.European child & adolescent psychiatry · 2025Observational
- Socioeconomic status and motor coordination function among children with autism.Frontiers in psychiatry · 2025Article
- Cluster analysis of motor coordination and health-related fitness in preschool children: population classification and variable contribution based on principal component analysis.Frontiers in public health · 2025Article
- Measurement of cognition and profiling early learning environments in India, Indonesia and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper.BMJ paediatrics open · 2024Article
- Everyday language input and production in 1,001 children from six continents.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Normative spatiotemporal fetal brain maturation with satisfactory development at 2 years.Nature · 2023Article
- The development of Brazilian women's and gender studies: a bibliometric diagnosis.Scientometrics · 2023Article
- Association between fetal abdominal growth trajectories, maternal metabolite signatures early in pregnancy, and childhood growth and adiposity: prospective observational multinational INTERBIO-21st fetal study.The lancet. Diabetes & endocrinology · 2022Observational
- A Community-based Responsive Caregiving Program Improves Neurodevelopment in Two-year Old Children in a Middle-Income Country, Grenada, West Indies.Psychosocial intervention · 2022Article
- Neurodevelopment in normocephalic children with and without prenatal Zika virus exposure.Archives of disease in childhood · 2022Article
- Complex Perinatal Syndromes Affecting Early Human Growth and Development: Issues to Consider to Understand Their Aetiology and Postnatal Effects.Frontiers in neuroscience · 2022Article
- Exposure of metal toxicity in Alzheimer's disease: An extensive review.Frontiers in pharmacology · 2022Review
- Africa is not a museum: the ethics of encouraging new parenting practices in rural communities in low-income and middle-income countries.BMJ global health · 2021Article
- Fetal growth velocity standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21American journal of obstetrics and gynecology · 2021Article
Corrections and comments
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Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is unclear whether early child development is, like skeletal growth, similar across diverse regions with adequate health and nutrition. We prospectively assessed 1307 healthy, well-nourished 2-year-old children of educated mothers, enrolled in early pregnancy from urban areas without major socioeconomic or environmental constraints, in Brazil, India, Italy, Kenya and UK. We used a specially developed psychometric tool, WHO motor milestones and visual tests. Similarities across sites were measured using variance components analysis and standardised site differences (SSD). In 14 of the 16 domains, the percentage of total variance explained by between-site differences ranged from 1.3% (cognitive score) to 9.2% (behaviour score). Of the 80 SSD comparisons, only six were >±0.50 units of the pooled SD for the corresponding item. The sequence and timing of attainment of neurodevelopmental milestones and associated behaviours in early childhood are, therefore, likely innate and universal, as long as nutritional and health needs are met.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.