Evidence map›Paper›PMID 30700514›Full record

ArticlemSphere2019

The Gut Microbiota Is Associated with Clearance of Clostridium difficile Infection Independent of Adaptive Immunity.

Jhansi L Leslie, Kimberly C Vendrov, Matthew L Jenior, Vincent B Young

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Attenuation ofJournal of microbiology and biotechnology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. The state of play of rodent models for the study ofJournal of medical microbiology · 2024
    Review
  9. Review
  10. Drug design, development and therapy · 2024
    Review
  11. Article
  12. Capturing the environment of the Clostridioides difficile infection cycle.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jhansi L LeslieDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-5600-210X
Kimberly C VendrovDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Matthew L JeniorDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0003-1884-3543
Vincent B YoungDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA youngvi@med.umich.edu.ORCID 0000-0003-3687-2364
University of Michigan · US

Funding

Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8M
Molecular Mechanisms of Microbial Pathogenesis Training ProgramT32AI007528 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 1998 to 2024
$6.8M
NIAID NIH HHS T32 AI007528NIAID NIH HHS U01 AI124255
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptive ImmunityGastrointestinal MicrobiomeMicrobial InteractionsAnimalsAntibody FormationClostridioides difficileClostridium InfectionsDisease Models, AnimalImmunity, CellularMiceadaptive immunityClostridium difficilecolonization resistanceintestinal colonizationmicrobiota

Identifiers

PMID30700514
PMCPMC6354811
OpenAlexW2952349596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.