ArticleBMC infectious diseases2019
Trend in risk of delay in diagnosis of new pulmonary tuberculosis in Northwest China from 2008 to 2017.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Analysis of factors influencing patient delay in tuberculosis patients in Northeast China: surveillance data from 2015 to 2024.BMC infectious diseases · 2026Article
- Cost-effectiveness of preventive treatment regimens for latent tuberculosis infection among key community-level populations.BMC medicine · 2025Article
- Assessing heterogeneity of patient and health system delay among TB in a population with internal migrants in China.Frontiers in public health · 2024Article
- Diagnostic delay, treatment duration and outcomes since the implementation of integrated model of tuberculosis control and their associated factors in a county in East China.BMC infectious diseases · 2023Article
- Trends of a decade in risk factors of patient delay among pulmonary tuberculosis patients during fast aging and urbanization - analysis of surveillance data from 2008 to 2017 in Wuhan, China.BMC public health · 2023Article
- Time-trend analysis of tuberculosis diagnosis in Shenzhen, China between 2011 and 2020.Frontiers in public health · 2023Article
- Comparison of Delay in Tuberculosis Diagnosis Between Migrants and Local Residents in an Eastern County of China: An Analysis of the Electronic Data Between 2015 and 2019.Frontiers in public health · 2021Article
- Determination of related factors about diagnostic and treatment delays in patients with smear-positive pulmonary tuberculosis in TurkeyTurkish journal of medical sciences · 2020Article
- Seasonal variation in notified tuberculosis cases from 2014 to 2018 in eastern China.The Journal of international medical research · 2020Article
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5 authors.
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Abstract
backgroundWith great changes over the past 10 years in China, especially the rapid economic development, population mobility, urbanization and aging, dynamic change on risk of delay, to our knowledge, has not been well studied in China. The study was to explore risk of delay in diagnosis of new pulmonary tuberculosis (PTB) and dynamic changes in risk of delay in Northwest China.
methodsFrom January 1, 2008 to December 31, 2017, a total of 13,603 people with new PTB registered in Yulin city of Shaanxi province were included. The median delay time was estimated by Kaplan-Meier survival curve. Time delay curves of year-, gender-year-, age-year- and smear-year specific were examined using log-rank test. Two-level mixed-effects survival model was used to calculate the hazard ratio (HR) and 95% confidence interval (95%CI) for factors associated with diagnostic delay. Time delay was defined as time interval between the onset of PTB symptoms and being diagnosed. The outcome variable of interest was defined as "being diagnosed" in survival analysis.
resultsThe 10-year delay time was 33 days (Interquartile Range, 16-65). Annual median delay time gradually decreased from 60 days to 33 days during the past 10 years. The probability that individuals were diagnosed since onset of PTB symptoms increased by 1.29 times in 2017 when compared to 2008. Female (Hazard Ratio (HR), 95%CI, 0.95(0.91-0.99)), age>45 years (HR, 95%CI, 0.87(0.82-0.93)) and smear positive (HR, 95%CI, 0.86(0.78-0.95)) were associated with increased risk of diagnostic delay over 10-year timespan. However, Age>45 years and smear positive showed trend to be protective factors in the past 5 years.
conclusionsTime and risk of delay in diagnosis of new PTB had declined over the past 10 years. However, more attentions should be paid to the fact that female still suffered from higher risk of diagnostic delay. We noted a potential reversal in traditional risk factors such as age>45 and smear positive. Those dynamic changes deserved further attention.
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