Evidence map›Paper›PMID 30700258›Full record

ArticleBMC infectious diseases2019

Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort.

Mahrrouz Caputo, Johannes Horn, André Karch, Manas K Akmatov, Heiko Becher, Bettina Braun, Hermann Brenner, Stefanie Castell, Beate Fischer, Guido Giani and 19 more

Open access · goldAbstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Vaccines for preventing herpes zoster in older adults.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Vaccines for preventing herpes zoster in older adults.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
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  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 18 institutions in 1 country.

Mahrrouz CaputoDepartment of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Johannes HornInstitute for Medical Epidemiology, Biometry, and Informatics (IMEBI), Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06110, Halle (Saale), Germany.
André KarchDepartment of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Manas K AkmatovDepartment of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Heiko BecherInstitute of Public Health, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany.
Bettina BraunInstitute for Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany.
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.
Stefanie CastellDepartment of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Beate FischerDepartment of Epidemiology and Preventive Medicine, University Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Guido GianiGerman Diabetes Center (DDZ), Leibniz Research for Diabetes, Auf'm Hennekamp 65, 40225, Düsseldorf, Germany.
Kathrin GüntherLeibniz Institute for Prevention Research and Epidemiology - BIPS, Achterstraße 30, 28359, Bremen, Germany.
Barbara HoffmannInstitute for Occupational, Social and Environmental Medicine, Heinrich-Heine-University of Düsseldorf, POB 101007, 40001, Düsseldorf, Germany.
Karl-Heinz JöckelInstitute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
Thomas KeilInstitute for Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Luisenstraße 57, 10117, Berlin, Germany.
Birgit KlüppelholzGerman Diabetes Center (DDZ), Leibniz Research for Diabetes, Auf'm Hennekamp 65, 40225, Düsseldorf, Germany.
Lilian KristInstitute for Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Luisenstraße 57, 10117, Berlin, Germany.
Michael F LeitzmannDepartment of Epidemiology and Preventive Medicine, University Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Wolfgang LiebInstitute of Epidemiology, Christian-Albrechts-University Kiel, Niemannsweg 11, 24105, Kiel, Germany.
Jakob LinseisenHelmholtz Zentrum Munich, German Research Center for Environmental Health, Institute of Epidemiology II, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Christa MeisingerHelmholtz Zentrum Munich, German Research Center for Environmental Health, Institute of Epidemiology II, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Susanne MoebusCentre of Urban Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
Nadia ObiDepartment of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Tobias PischonMolecular Epidemiology Research Group, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin-Buch, Germany.
Sabine SchipfInstitute for Community Medicine, University Medicine Greifswald, University Medicine Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Germany.
Börge SchmidtInstitute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
Claudia SieversDepartment of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Astrid SteinbrecherMolecular Epidemiology Research Group, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin-Buch, Germany.
Henry VölzkeInstitute for Community Medicine, University Medicine Greifswald, University Medicine Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Germany.
Rafael MikolajczykInstitute for Medical Epidemiology, Biometry, and Informatics (IMEBI), Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06110, Halle (Saale), Germany. rafael.mikolajczyk@uk-halle.de.
Helmholtz Centre for Infection Research · DEInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DECharité - Universitätsmedizin Berlin · DEDeutsches Diabetes-Zentrum e.V. · DEGerman Center for Infection Research · DEMax Delbrück Center · DEUniversitätsmedizin Greifswald · DEUniversity of Regensburg · DEChristian-Albrechts-Universität zu Kiel · DEHeidelberg University · DEHeinrich Heine University Düsseldorf · DEHelmholtz Zentrum München · DELeibniz Institute for Prevention Research and Epidemiology - BIPS · DELudwig-Maximilians-Universität München · DEMartin Luther University Halle-Wittenberg · DEUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUntil now, herpes zoster (HZ)-related disease burden in Germany has been estimated based on health insurance data and clinical findings. However, the validity of self-reported HZ is unclear. This study investigated the validity of self-reported herpes zoster (HZ) and its complication postherpetic neuralgia (PHN) using data from the pretest studies of the German National Cohort (GNC) in comparison with estimates based on health insurance data.

methodsData of 4751 participants aged between 20 and 69 years from two pretest studies of the GNC carried out in 2011 and 2012 were used. Based on self-reports of physician-diagnosed HZ and PHN, age- and sex-specific HZ incidence rates and PHN proportions were estimated. For comparison, estimates based on statutory health insurance data from the German population were considered.

resultsEleven percent (95%-CI, 10.4 to 12.3, n = 539) of the participants reported at least one HZ episode in their lifetime. Our estimated age-specific HZ incidence rates were lower than previous estimates based on statutory health insurance data. The PHN proportion in participants older than 50 years was 5.9% (1.9 to 13.9%), which was in line with estimates based on health insurance data.

conclusionAs age- and sex-specific patterns were comparable with that in health insurance data, self-reported diagnosis of HZ seems to be a valid instrument for overall disease trends. Possible reasons for observed differences in incidence rates are recall bias in self-reported data or overestimation in health insurance data.

Indexed as

Self ReportAdultAgedAge FactorsCohort StudiesFemaleGermanyHerpesvirus 3, HumanHerpes ZosterHumansIncidenceMaleMiddle AgedNeuralgia, PostherpeticReproducibility of ResultsSex FactorsGerman National CohortHerpes zosterIncidencePostherpetic neuralgiaSelf-reportsValidity

Identifiers

PMID30700258
PMCPMC6354372
OpenAlexW2947803854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.