ArticleBMC plant biology2019
Physiological and iTRAQ-based proteomic analyses reveal the function of exogenous γ-aminobutyric acid (GABA) in improving tea plant (Camellia sinensis L.) tolerance at cold temperature.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 110 citations in OpenAlex.
- Growth-Phase-Dependent Shift in GABA Biosynthetic Pathways Under Temperature Stress inMicroorganisms · 2026Article
- Physiological Responses in the Hepatopancreas ofAntioxidants (Basel, Switzerland) · 2026Article
- Review
- Comparative physiological and transcriptome analyzes reveal the function of exogenous dopamine in improving the tolerance to salt stress inFrontiers in plant science · 2026Article
- Characteristic Analysis of Metabolic Profiles ofMetabolites · 2025Article
- Transcriptional regulation of SlFRIGIDA-like improve antioxidant system in tomato under cold.BMC plant biology · 2025Article
- Gamma-Aminobutyric Acid: A Novel Biomolecule to Improve Plant Resistance and Fruit Quality.Plants (Basel, Switzerland) · 2025Review
- Plant resistance inducer AMHA enhances antioxidant capacities to promote cold tolerance by regulating the upgrade of glutathione S-transferase in tea plant.Horticulture research · 2025Article
- Molecular Mechanism of Exogenous GABA in Regulating Salt Tolerance in Tomato (International journal of molecular sciences · 2025Article
- Review
- Review
- Transcriptomic and metabolomic analysis reveal the cold tolerance mechanism of common beans under cold stress.BMC plant biology · 2025Article
- Effects of low temperature stress on photosynthetic characteristics and antioxidant defense system of flue-cured tobacco.Frontiers in plant science · 2025Article
- Relationship between the GABA Pathway and Signaling of Other Regulatory Molecules.International journal of molecular sciences · 2024Review
- Integrated transcriptomic and metabolomic data reveal the cold stress responses molecular mechanisms of two coconut varieties.Frontiers in plant science · 2024Article
- Mechanism of Salt Tolerance and Plant Growth Promotion inInternational journal of molecular sciences · 2023Article
- Role of Gamma-Aminobutyric Acid in Plant Defense Response.Metabolites · 2023Review
- Integrated Metabolomic and Transcriptomic Analysis Reveals That Amino Acid Biosynthesis May Determine Differences in Cold-Tolerant and Cold-Sensitive Tea Cultivars.International journal of molecular sciences · 2023Article
- Recent progress and perspectives on physiological and molecular mechanisms underlying cold tolerance of tea plants.Frontiers in plant science · 2023Review
- Multi-omics research on common allergens during the ripening of pollen and poplar flocs ofFrontiers in plant science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundInternal γ-Aminobutyric Acid (GABA) interacting with stress response substances may be involved in the regulation of differentially abundant proteins (DAPs) associated with optimum temperature and cold stress in tea plants (Camellia sinensis (L.) O. Kuntze).
resultsTea plants supplied with or without 5.0 mM GABA were subjected to optimum or cold temperatures in this study. The increased GABA level induced by exogenous GABA altered levels of stress response substances - such as glutamate, polyamines and anthocyanins - in association with improved cold tolerance. Isobaric tags for relative and absolute quantification (iTRAQ) - based DAPs were found for protein metabolism and nucleotide metabolism, energy, amino acid transport and metabolism other biological processes, inorganic ion transport and metabolism, lipid metabolism, carbohydrate transport and metabolism, biosynthesis of secondary metabolites, antioxidant and stress defense.
conclusionsThe iTRAQ analysis could explain the GABA-induced physiological effects associated with cold tolerance in tea plants. Analysis of functional protein-protein networks further showed that alteration of endogenous GABA and stress response substances induced interactions among photosynthesis, amino acid biosynthesis, and carbon and nitrogen metabolism, and the corresponding differences could contribute to improved cold tolerance of tea plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.