Evidence map›Paper›PMID 30699971›Full record

Trial reportNutrients2019

Blueberries Improve Pain, Gait Performance, and Inflammation in Individuals with Symptomatic Knee Osteoarthritis.

Chen Du, Amy Smith, Marco Avalos, Sanique South, Keith Crabtree, Wanyi Wang, Young-Hoo Kwon, Parakat Vijayagopal, Shanil Juma

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 7 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 7 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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  17. [Dietary inflammatory index related to knee osteoarthritis symptomatology].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chen DuDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. cdu@twu.edu.
Amy SmithDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. asmith60@twu.edu.
Marco AvalosSchool of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA. mavalos1@twu.edu.ORCID 0000-0001-5724-0919
Sanique SouthDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. ssouth@twu.edu.
Keith CrabtreeDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. kcrabtree@twu.edu.
Wanyi WangCenter for Research Design and Analysis, Texas Woman's University, Houston, TX 77030, USA. WWang@twu.edu.ORCID 0000-0001-9482-9968
Young-Hoo KwonSchool of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA. YKwon@twu.edu.
Parakat VijayagopalDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. pvijayagopal@twu.edu.
Shanil JumaDepartment of Nutrition and Food Science, Texas Woman's University, Denton, TX 76204, USA. sjuma@twu.edu.
Texas Woman's University · US

Funding

US Highbush Blueberry Council N/A
6 · The paper itself

Abstract

Osteoarthritis (OA) is the most common joint disorder in the world and is the most frequent cause of walking related disability among older adults in the US, which brings a significant economic burden and reduces quality of life. The initiation and development of OA typically involves degeneration or progressive loss of the structure and function of articular cartilage. Inflammation is one of the major drives of the progression of OA. Dietary polyphenols have been studied for their anti-inflammatory properties and potential anabolic effects on the cartilage cells. Blueberries are widely consumed and are high in dietary polyphenols, therefore regular consumption of blueberries may help improve OA. The purpose of the present study was to examine the effect of freeze dried whole blueberries on pain, gait performance, and inflammation in individuals with symptomatic knee OA. In a randomized, double-blind trial, adults age 45 to 79 with symptomatic knee OA, were randomized to either consume 40 g freeze-dried blueberry powder (

Indexed as

Blueberry PlantsGaitAgedDouble-Blind MethodFemaleHumansInflammationInflammation MediatorsMaleMiddle AgedOsteoarthritis, KneePainPain MeasurementWalkingInflammation Mediatorsblueberrygaitinflammationknee osteoarthritispainpolyphenols

Identifiers

PMID30699971
PMCPMC6413191
OpenAlexW2912155168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.