Evidence map›Paper›PMID 30699942›Full record

ReviewCancers2019

Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients.

Philipp Lohmann, Jan-Michael Werner, N Jon Shah, Gereon R Fink, Karl-Josef Langen, Norbert Galldiks

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Prediction of Glioma Grade and IDH Status UsingDiagnostics (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Application of Metabolic Reprogramming to Cancer Imaging and Diagnosis.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Review
  15. Enzymatic synthesis of fluorinated compounds.Applied microbiology and biotechnology · 2021
    Review
  16. Review
  17. Review
  18. Review
  19. Maximizing the use of batch production ofNeuro-oncology practice · 2021
    Article
  20. Frontiers in oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Philipp LohmannInstitute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany. p.lohmann@fz-juelich.de.ORCID 0000-0002-5360-046X
Jan-Michael WernerDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany. jan-michael.werner@uk-koeln.de.ORCID 0000-0001-7147-4594
N Jon ShahInstitute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany. n.j.shah@fz-juelich.de.
Gereon R FinkInstitute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany. gereon.fink@uk-koeln.de.
Karl-Josef LangenInstitute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany. k.j.langen@fz-juelich.de.
Norbert GalldiksInstitute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany. n.galldiks@fz-juelich.de.
Forschungszentrum Jülich · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI) provide valuable information about brain tumor patients. Particularly amino acid PET, advanced MRI techniques, and combinations thereof are of great interest for the non-invasive assessment of biological characteristics in patients with primary or secondary brain cancer. A methodological innovation that potentially advances research in patients with brain tumors is the increasing availability of hybrid PET/MRI systems, which enables the simultaneous acquisition of both imaging modalities. Furthermore, the advent of ultra-high field MRI scanners operating at magnetic field strengths of 7 T or more will allow further development of metabolic MR imaging at higher resolution. This review focuses on the combination of amino acid PET with MR spectroscopic imaging, perfusion- and diffusion-weighted imaging, as well as chemical exchange saturation transfer in patients with high-grade gliomas, especially glioblastomas.

Indexed as

[11C]-methyl-l-methionine (MET)3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (FDOPA)brain tumorschemical exchange saturation transferdiffusion-weighted imaginghigh-grade gliomahybrid PET/MRI scannermagnetic resonance spectroscopyO-(2-[18F]-fluoroethyl)-l-tyrosine (FET)perfusion-weighted imaging

Identifiers

PMID30699942
PMCPMC6406895
OpenAlexW2913953166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.