Evidence map›Paper›PMID 30699915›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Self-Assembling Hybrid Linear-Dendritic Block Copolymers: The Design of Nano-Carriers for Lipophilic Antitumoral Drugs.

Elisabetta Fedeli, Alexandre Lancelot, Juan Manuel Dominguez, José Luis Serrano, Pilar Calvo, Teresa Sierra

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisabetta FedeliDepartamento de Química Orgánica, Instituto de Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Edificio I+D, Universidad de Zaragoza, 50018 Zaragoza, Spain. elife83@gmail.com.
Alexandre LancelotDepartamento de Química Orgánica, Instituto de Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Edificio I+D, Universidad de Zaragoza, 50018 Zaragoza, Spain. alexandrelancelot@gmail.com.ORCID 0000-0002-9213-9186
Juan Manuel DominguezPharmaMar S.A., 28770 Colmenar Viejo, Madrid, Spain. jmdominguez@pharmamar.com.
José Luis SerranoDepartamento de Química Orgánica, Instituto de Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Edificio I+D, Universidad de Zaragoza, 50018 Zaragoza, Spain. joseluis@unizar.es.
Pilar CalvoPharmaMar S.A., 28770 Colmenar Viejo, Madrid, Spain. pcalvo@pharmamar.com.
Teresa SierraDepartamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón (ICMA), Facultad de Ciencias, CSIC, Universidad de Zaragoza, 50009 Zaragoza, Spain. tsierra@unizar.es.ORCID 0000-0001-7091-077X

Funding

FP7 People: Marie-Curie Actions 215884-2Gobierno de Aragón E47_17RMinisterio de Economía, Industria y Competitividad, Gobierno de España CTQ2015-70174-PMinisterio de Economía, Industria y Competitividad, Gobierno de España MAT2015-66208-C3-1-PMinisterio de Educación, Cultura y Deporte 12/05210
6 · The paper itself

Abstract

Two series of amphiphilic block copolymers with a hybrid linear-dendritic structure are presented. The compounds consisted of a hydrophilic poly (ethylene glycol) (PEG) block and a 2,2'-bis(hydroxymethyl)propionic acid (bis-MPA) dendron functionalized with stearic acid chains that impart a hydrophobic nature to the block. Different self-assembled nanostructures with a hydrophobic interior and a hydrophilic external part were obtained depending on the length of the PEG chain (

Indexed as

anticancerdendrimersdrug deliverymicellar aggregates

Identifiers

PMID30699915
PMCPMC6409548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.