Evidence map›Paper›PMID 30699912›Full record

ArticleViruses2019

Characterization of Host and Bacterial Contributions to Lung Barrier Dysfunction Following Co-infection with 2009 Pandemic Influenza and Methicillin Resistant

Michaela E Nickol, Justine Ciric, Shane D Falcinelli, Daniel S Chertow, Jason Kindrachuk

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  13. Article
  14. Immunopathogenesis of COVID-19 and early immunomodulators.Clinical and experimental pediatrics · 2020
    Article
  15. Article
  16. Frontiers in cellular and infection microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Michaela E NickolLaboratory of Emerging and Re-Emerging Viruses, Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada. nickolm@myumanitoba.ca.
Justine CiricLaboratory of Emerging and Re-Emerging Viruses, Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada. ciricj@myumanitoba.ca.
Shane D FalcinelliDepartment of Microbiology and Immunology, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. shane_falcinelli@med.unc.edu.ORCID 0000-0002-3554-226X
Daniel S ChertowLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. chertowd@cc.nih.gov.ORCID 0000-0002-1675-1728
Jason KindrachukLaboratory of Emerging and Re-Emerging Viruses, Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada. Jason.Kindrachuk@umanitoba.ca.ORCID 0000-0002-3305-7084
University of Manitoba · CANational Institutes of Health · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza viruses are a threat to global public health resulting in ~500,000 deaths each year. Despite an intensive vaccination program, influenza infections remain a recurrent, yet unsolved public health problem. Secondary bacterial infections frequently complicate influenza infections during seasonal outbreaks and pandemics, resulting in increased morbidity and mortality.

Indexed as

A549 CellsAlveolar Epithelial CellsBlood-Air BarrierCoinfectionHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLungMethicillin-Resistant Staphylococcus aureusProtein Array AnalysisStaphylococcal InfectionsVirulence FactorsVirus ReplicationVirulence Factors2009 pandemicalveolar epithelial cellsbarrier functionco-infectioninfluenzakinomeStaphylococcus aureusvirulence factors

Identifiers

PMID30699912
PMCPMC6409999
OpenAlexW2912505580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.