Evidence map›Paper›PMID 30698902›Full record

ArticleAddiction (Abingdon, England)2019

Patterns of social determinants of health associated with drug use among women living with HIV in Canada: a latent class analysis.

Mostafa Shokoohi, Greta R Bauer, Angela Kaida, Carmen H Logie, Ashley Lacombe-Duncan, M-J Milloy, Elisa Lloyd-Smith, Allison Carter, Mona Loutfy, CHIWOS Research Team

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Psychometric Properties of the Berger HIV Stigma Scale: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
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  7. Drug misuse, self-esteem, and intimate partner violence among low-income African American women.Psychological trauma : theory, research, practice and policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mostafa ShokoohiEpidemiology and Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON, Canada.ORCID 0000-0002-3810-752X
Greta R BauerEpidemiology and Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON, Canada.
Angela KaidaFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Carmen H LogieFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Ashley Lacombe-DuncanSchool of Social Work, University of Michigan, Ann Arbor, Michigan, USA.
M-J MilloyBritish Columbia Centre on Substance Use, St. Paul's Hospital, Vancouver, BC, Canada.ORCID 0000-0003-3821-6221
Elisa Lloyd-SmithVancouver Coastal Health, Vancouver, British Columbia, Canada.
Allison CarterFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Mona LoutfyWomen's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
CHIWOS Research Team

Funding

Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
Academic Health Science Centres (AHSC) Alternative Funding Plans (AFP) Innovation FundCanadian Institutes of Health Research (CIHR) FDN154325Canadian Institutes of Health Research (CIHR) MOP-111041CIHR Canadian HIV Trials Network CTN 262NIDA NIH HHS U01 DA021525Ontario HIV Treatment Network
6 · The paper itself

Abstract

BACKGROUND AND

aimsIdentifying typologies of social determinants of health (SDoH) vulnerability influencing drug use practices among women living with HIV (WLWH) can help to address associated harms. This research aimed to explore the association of SDoH clusters with drug use among WLWH.

designLatent class analysis (LCA) was used to identify the distinct clusters of SDoH. Inverse probability weighting (IPW) was employed to account for confounding and potential selection bias. Associations were analyzed using generalized linear model with log link and Poisson distribution, and then weighted risk ratio (RR) and 95% confidence intervals (CI) were reported. SETTING AND

participantsData from 1422 WLWH recruited at time-point 1 of the Canadian HIV Women's Sexual and Reproductive Health Cohort Study (CHIWOS, 2013-15), with 1252 participants at 18 months follow-up (time-point 2). MEASUREMENTS: Drug use was defined as use of illicit/non-prescribed opioids/stimulants in the past 6 months. SDoH indicators included: race discrimination, gender discrimination, HIV stigma, social support, access to care, food security, income level, employment status, education, housing status and histories of recent sex work and incarceration.

findingsLCA identified four SDoH classes: no/least SDoH adversities (6.6%), discrimination/stigma (17.7%), economic hardship (30.8%) and most SDoH adversities (45.0%). Drug use was reported by 17.5% and 17.2% at time-points 1 and 2, respectively. WLWH with no/least SDoH adversities were less likely to report drug use than those in economic hardship class (weighted RR = 0.13; 95% CIs = 0.03, 0.63), discrimination/stigma class (weighted RR = 0.15; 95% CIs = 0.03, 0.78), and most SDoH adversities class (weighted RR = 0.13; 95% CIs = 0.03, 0.58).

conclusionsSocial determinants of health vulnerabilities are associated with greater likelihood of drug use, underscoring the significance of addressing interlinked social determinants and drug use through the course of HIV care and treatment.

Indexed as

HIV InfectionsSocial StigmaSocial SupportAdultCanadaEducational StatusEmploymentFemaleFood SupplyHealth Services AccessibilityHousingHumansIncomeLatent Class AnalysisLinear ModelsMiddle AgedCanadaCHIWOSdrug useHIVsocial determinantswomen

Identifiers

PMID30698902
PMCPMC6992379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.