ArticleThe Laryngoscope2019
Feasibility and tolerability of measuring translaryngeal pressure during exercise.
Article in The Laryngoscope, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04620343 (Exercise Induced Laryngeal Obstruction; a Randomized Controlled Treatment Trial), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise Induced Laryngeal Obstruction; a Randomized Controlled Treatment Trial
Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Inspiratory and expiratory tracheal pressures during high-intensity exercise in harness racehorses.Equine veterinary journal · 2026Article
- Objective diagnosis of alar fold collapse in active Standardbred trotting racehorses using nasopharyngeal airway pressure measurements.Equine veterinary journal · 2026Article
- Exploring upper airway and laryngeal resistance to noninvasive ventilation in healthy awake adults.Physiological reports · 2025Article
- A speech therapy treatment protocol for exercise induced laryngeal obstruction.Frontiers in pediatrics · 2024Article
- Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'.British journal of sports medicine · 2022Review
- Reliability of translaryngeal airway resistance measurements during maximal exercise.ERJ open research · 2022Article
- Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial.Frontiers in pediatrics · 2022Article
- Is the healthy respiratory system built just right, overbuilt, or underbuilt to meet the demands imposed by exercise?Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Severe Exercise-Induced Laryngeal Obstruction Treated With Supraglottoplasty.Frontiers in surgery · 2019Article
- Exercise Induced Laryngeal Obstruction in Humans and Equines. A Comparative Review.Frontiers in physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectives/hypothesisTo determine if simultaneous tracheal and supraglottic pressure measurement performed during a continuous laryngoscopy exercise (CLE) test is possible, tolerable, and feasible, and if so, whether measurements can be used to determined airflow resistance over the larynx, thus providing an objective outcome measure for the CLE test, the gold standard for diagnosing exercise-induced laryngeal obstruction. STUDY
designExplorative descriptive clinical study.
methodsA CLE test was performed with the addition of two pressure sensors (Mikro-Cath 825-0101; Millar, Houston, TX) placed at the epiglottic tip and at the fifth tracheal ring. To place sensors, laryngeal anesthesia and a channel scope were required. Tolerability and feasibility was determined by a Likert score and subjective indication from subjects and operators. Adjustments to the technique were made to increase tolerability. The pressure data were continuously collected and analyzed for artifacts, drifts, frequency response, and used with flow data to calculate translaryngeal resistance.
resultsAll subjects (n = 7) completed all procedures. Two main areas of concern were identified regarding tolerability: application of topical anesthesia to the larynx and nasal discomfort due to the added diameter of the laryngoscope. Protocol adjustments improved both. Pressure data were obtained from all procedures in all subjects, were consistent, and followed physiological trends.
conclusionsContinuous measurement of the translaryngeal pressure gradient during a CLE test is possible, feasible, and tolerable. A CLE test with direct measurement of the translaryngeal pressure gradient might become a valuable tool in the objective assessment of respiratory function, and normal values should be established in health and disease. LEVEL OF EVIDENCE: NA Laryngoscope, 129:2748-2753, 2019.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.