Evidence map›Paper›PMID 30698794›Full record

ArticleThe Journal of infectious diseases2019

Plasmodium vivax Relapse Rates Following Plasmodium falciparum Malaria Reflect Previous Transmission Intensity.

Elizabeth A Ashley, Aung Pyae Phyo, Verena I Carrara, Kyaw Myo Tun, Francois Nosten, Frank Smithuis, Nicholas J White

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. Open forum infectious diseases · 2026
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  11. RecurrentInternational journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth A AshleyMyanmar Oxford Clinical Research Unit, Myanmar.
Aung Pyae PhyoMyanmar Oxford Clinical Research Unit, Myanmar.
Verena I CarraraShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot.
Kyaw Myo TunDepartment of Preventive and Social Medicine, Defence Services Medical Academy.
Francois NostenCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.
Frank SmithuisMyanmar Oxford Clinical Research Unit, Myanmar.
Nicholas J WhiteCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

From 2003 through 2009, 687 of 2885 patients (23.8%) treated for Plasmodium falciparum malaria in clinical studies in Myanmar or on the Thailand-Myanmar border had recurrent Plasmodium vivax malaria within 63 days, compared with 18 of 429 patients (4.2%) from 2010 onward (risk ratio [RR], 0.176; 95% confidence interval, .112-.278; P < .0001). Corresponding data from 42 days of follow-up revealed that 820 of 3883 patients (21.1%) had recurrent P. vivax malaria before 2010, compared with 22 of 886 (2.5%) from 2010 onward (RR, 0.117; 95% CI, .077-.177; P < .0001). This 6-fold reduction suggests a recent decline in P. vivax transmission intensity and, thus, a substantial reduction in the proportion of individuals harboring hypnozoites.

Indexed as

AdultChildFemaleHumansMalaria, FalciparumMalaria, VivaxMaleMyanmarPlasmodium falciparumPlasmodium vivaxRecurrenceThailandMalariaP. falciparumP. vivaxrelapse

Identifiers

PMID30698794
PMCPMC6548896

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.