ArticleEpidemiology and psychiatric sciences2019
Network analysis of the relationship between depressive symptoms, demographics, nutrition, quality of life and medical condition factors in the Osteoarthritis Initiative database cohort of elderly North-American adults with or at risk for osteoarthritis.
Article in Epidemiology and psychiatric sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
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- Multidimensional analysis of the clinical spectrum and symptom burden of unexplained myofascial pain.medRxiv : the preprint server for health sciences · 2026Article
- Prevalence and factors associated with sarcopenia risk among older adults with diabetes: an exploratory network analysis.BMC geriatrics · 2025Article
- Cross-sectional and longitudinal relationships between COVID-19 stressors and depressive symptoms across sex and age groups: findings from the Canadian longitudinal study on aging.Epidemiology and psychiatric sciences · 2025Article
- Network Analysis of Depressive Symptoms and Meaning in Life and Their Association with Health-Related Quality of Life Among South Korean Older Adults.Healthcare (Basel, Switzerland) · 2025Article
- Multidimensional links between dietary behavior and cardiometabolic comorbidities: a network analysis.Diabetology & metabolic syndrome · 2025Article
- A longitudinal study of dietary inflammatory index and quality of life in people with osteoarthritis: data from the Osteoarthritis Initiative database.Scientific reports · 2025Article
- Network analysis of demographics, dietary habits and health-related quality of life among northern Chinese population.BMJ public health · 2025Article
- The Associations of Exposome Score with Various Domains of Psychopathology: A Network Analysis in a Non-Clinical Sample.Brain sciences · 2024Article
- Investigating the Physical and Mental Health Nexus: a Network Analysis of Depression, Cardiometabolic Health, Bone Mass, and Perceived Health Status Among Filipino Domestic Workers.International journal of behavioral medicine · 2023Article
- Bridge connection between depression and anxiety symptoms and lifestyles in Chinese residents from a network perspective.Frontiers in psychiatry · 2023Article
- The Ripple Effect: Unveiling the Bidirectional Relationship Between Negative Life Events and Depressive Symptoms in Medical Cadets.Psychology research and behavior management · 2023Article
- Eating disorder psychopathology and negative affect in Iranian college students: a network analysis.Journal of eating disorders · 2022Article
- The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic.Journal of affective disorders · 2022Article
- Identification for heavy metals exposure on osteoarthritis among aging people and Machine learning for prediction: A study based on NHANES 2011-2020.Frontiers in public health · 2022Article
- Monthly Disposable Income Is a Crucial Factor Affecting the Quality of Life in Patients with Knee Osteoarthritis.Healthcare (Basel, Switzerland) · 2021Article
- Article
- The psychometric network structure of mental health in eating disorder patients.European eating disorders review : the journal of the Eating Disorders Association · 2021Article
- Discovery of Depression-Associated Factors From a Nationwide Population-Based Survey: Epidemiological Study Using Machine Learning and Network Analysis.Journal of medical Internet research · 2021Article
- Factors Associated with Non-Adherence to Drugs in Patients with Chronic Diseases Who Go to Pharmacies in Spain.International journal of environmental research and public health · 2021Observational
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsA complex interaction exists between age, body mass index, medical conditions, polypharmacotherapy, smoking, alcohol use, education, nutrition, depressive symptoms, functioning and quality of life (QoL). We aimed to examine the inter-relationships among these variables, test whether depressive symptomology plays a central role in a large sample of adults, and determine the degree of association with life-style and health variables.
methodsRegularised network analysis was applied to 3532 North-American adults aged ⩾45 years drawn from the Osteoarthritis Initiative. Network stability (autocorrelation after case-dropping), centrality of nodes (strength, M, the sum of weight of the connections for each node), and edges/regularised partial correlations connecting the nodes were assessed.
resultsPhysical and mental health-related QoL (M = 1.681; M = 1.342), income (M = 1.891), age (M = 1.416), depressive symptoms (M = 1.214) and education (M = 1.173) were central nodes. Depressive symptoms' stronger negative connections were found with mental health-related QoL (-0.702), income (-0.090), education (-0.068) and physical health-related QoL (-0.354). This latter was a 'bridge node' that connected depressive symptoms with Charlson comorbidity index, and number of medications. Physical activity and Mediterranean diet adherence were associated with income and physical health-related QoL. This latter was a 'bridge node' between the former two and depressive symptoms. The network was stable (stability coefficient = 0.75, i.e. highest possible value) for all centrality measures.
conclusionsA stable network exists between life-style behaviors and social, environmental, medical and psychiatric variables. QoL, income, age and depressive symptoms were central in the multidimensional network. Physical health-related QoL seems to be a 'bridge node' connecting depressive symptoms with several life-style and health variables. Further studies should assess such interactions in the general population.
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