Evidence map›Paper›PMID 30698457›Full record

ArticleAnnals of the Royal College of Surgeons of England2019

Risk factors for surgical site infections in neurosurgery.

S Patel, D Thompson, S Innocent, V Narbad, R Selway, K Barkas

Abstract read
In one paragraph

Article in Annals of the Royal College of Surgeons of England, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S PatelKing's College NHS Foundation Trust , UK.
D ThompsonKing's College NHS Foundation Trust , UK.
S InnocentKing's College London , UK.
V NarbadKing's College NHS Foundation Trust , UK.
R SelwayKing's College NHS Foundation Trust , UK.
K BarkasKing's College NHS Foundation Trust , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurgical site infections (SSIs) are of profound significance in neurosurgical departments, resulting in high morbidity and mortality. There are limited public data regarding the incidence of SSIs in neurosurgery. The aim of this study was to determine the rate of SSIs (particularly those requiring reoperation) over a seven-year period and identify factors leading to an increased risk.

methodsAn age matched retrospective analysis was undertaken of a series of 16,513 patients at a single centre. All patients who required reoperation for suspected SSIs within a 7-year period were identified. Exclusion criteria comprised absence of infective material intraoperatively and patients presenting with primary infections. Clinical notes were reviewed to confirm presence or absence of suspected risk factors.

resultsOf the 16,513 patients in the study, 1.20% required at least one further operation to treat a SSI. Wound leak (odds ratio [OR]: 27.41), dexamethasone use (OR: 3.55), instrumentation (OR: 2.74) and operative duration >180 minutes (OR: 1.85) were statistically significant risk factors for reoperation.

conclusionsThis is the first UK study of such a duration that has documented a SSI reoperation rate in a cohort of this size. Various risk factors are associated with the development of SSIs, making it essential to have robust auditing and monitoring of high risk patients to ensure excellent standards of healthcare. Departmental and public registers to record all SSIs may be beneficial, particularly for those treated solely by general practitioners, allowing units to address potential risk factors prior to surgical intervention.

Indexed as

Operative TimeAdultCase-Control StudiesDexamethasoneElectronic Health RecordsFemaleGlucocorticoidsHumansIncidenceMaleMedical AuditMiddle AgedNeurosurgeryNeurosurgical ProceduresReoperationRetrospective StudiesDexamethasoneGlucocorticoidsRisk factorsSurgical site infectionWound infectionWound leak

Identifiers

PMID30698457
PMCPMC6400918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.