Evidence map›Paper›PMID 30698303›Full record

ArticleHead & neck2019

Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000.

Samantha Lang, Sarah Schimansky, Rhona Beynon, Christopher Penfold, Amy Davies, Andrea Waylen, Steven Thomas, Miranda Pring, Michael Pawlita, Tim Waterboer and 1 more

Abstract read
In one paragraph

Article in Head & neck, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samantha LangNational Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-8662-6386
Sarah SchimanskyNational Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-7539-2104
Rhona BeynonDepartment of Population Health Sciences, University of Bristol Medical School, Bristol, United Kingdom.
Christopher PenfoldNational Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-8654-353X
Amy DaviesNational Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.
Andrea WaylenDepartment of Oral and Dental Sciences, Bristol Dental School, Bristol, United Kingdom.
Steven ThomasDepartment of Oral and Dental Sciences, Bristol Dental School, Bristol, United Kingdom.
Miranda PringDepartment of Oral and Dental Sciences, Bristol Dental School, Bristol, United Kingdom.
Michael PawlitaMolecular Diagnostics of Oncogenic Infections Division, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Tim WaterboerInfections and Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Andrew R NessNational Institute of Health (NIHR) Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, United Kingdom.

Funding

Cancer Research UK 19169Cancer Research UK A19169Cancer Research UK C18281Department of Health RP-PG-0707-10034
6 · The paper itself

Abstract

backgroundThe association between diet and head and neck cancer (HNC) survival is unclear.

methodsCox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.

resultsFruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).

conclusionsVegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.

Indexed as

DietFruitVegetablesAgedAged, 80 and overAlcohol DrinkingCohort StudiesFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedProportional Hazards ModelsSmokingUnited Kingdomdeep-fried foodfruithead and neck cancerssurvivalvegetables

Identifiers

PMID30698303
PMCPMC7116031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.