ReviewExpert review of anti-infective therapy2019
Ocular Chlamydia trachomatis infection: elimination with mass drug administration.
Review in Expert review of anti-infective therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Prevalence and Historical Trends of Trachoma in Egypt: A Systematic Review and Meta-Analysis.The Yale journal of biology and medicine · 2025Pooled it
- Comparison of School-Based and Community-Wide Mass Drug Administration for Schistosomiasis Control in an Area of Western Kenya with High InitialThe American journal of tropical medicine and hygiene · 2020Trial
- Computational design of a novel chimeric multi-epitope vaccine against chlamydia trachomatis serovar a to prevent trachoma.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Assessing the effectiveness of the community participation approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Baringo County, Kenya.PLoS neglected tropical diseases · 2025Article
- Prevalence of Chlamydia trachomatis in eye specimens of patients suspected of having viral keratitis: a cross-sectional study.New microbes and new infections · 2025Article
- Ongoing transmission of trachoma in low prevalence districts in Mozambique: results from four cross-sectional enhanced impact surveys, 2022.Scientific reports · 2024Article
- Genomic insights into local-scale evolution of ocularMicrobial genomics · 2024Article
- Insights into innate immune cell evasion byFrontiers in immunology · 2024Review
- Gender differences in trachomatous scarring prevalence in a formerly trachoma hyperendemic district in Tanzania.PLoS neglected tropical diseases · 2024Article
- Expanding a photographic grading system for trachomatous scarring.International health · 2023Article
- Prevalence of Trachoma after Implementation of Trachoma Elimination Interventions in Oromia Regional State, Ethiopia: Results of Impact Surveys in 131 Evaluation Units Covering 139 Districts.Ophthalmic epidemiology · 2023Article
- Risk factors for the progression of trachomatous scarring in a cohort of women in a trachoma low endemic district in Tanzania.PLoS neglected tropical diseases · 2021Article
- Designing a Multi-Epitope Vaccine againstBiology · 2021Article
- Environmental factors and hygiene behaviors associated with facial cleanliness and trachoma in Kongwa, Tanzania.PLoS neglected tropical diseases · 2021Article
- Children as messengers of health knowledge? Impact of health promotion and water infrastructure in schools on facial cleanliness and trachoma in the community.PLoS neglected tropical diseases · 2021Article
- Patient perceived barriers to surgical follow-up: Study of 6-month post-operative trichiasis surgery follow-up in Tanzania.PloS one · 2021Article
- Effectiveness and safety of azithromycin 1.5% eye drops for mass treatment of active trachoma in a highly endemic district in Cameroon.BMJ open ophthalmology · 2020Article
- Toward the Elimination of Disease: the 2019 Weisenfeld Award Lecture.Investigative ophthalmology & visual science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
introductionOcular Chlamydia trachomatis infection, the causative agent for trachoma, is responsible for 1.9 million cases of visual loss worldwide. Mass Drug Administration (MDA) with azithromycin to entire trachoma-endemic districts is part of the World Health Organization's public health strategy for trachoma elimination. Areas covered: Background on C. trachomatis and the epidemiology of trachoma are presented, followed by a review of the antibiotics for treatment and the need for a public health approach to trachoma elimination. The effectiveness of mass drug administration is presented, concluding with challenges to trachoma elimination in the future. Expert opinion: MDA using azithromycin is a key component of the public health strategy for trachoma elimination. With high coverage in children, there is good evidence that MDA drops the community pool of infection. There are challenges to trachoma elimination by the year 2020, and the drug donation program for country MDAs will be integral to ongoing efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.