Evidence map›Paper›PMID 30697813›Full record

ArticleMagnetic resonance in medicine2019

Improved chemical exchange saturation transfer imaging with real-time frequency drift correction.

Ruibin Liu, Hongxi Zhang, Weiming Niu, Can Lai, Qiuping Ding, Weibo Chen, Sayuan Liang, Jinyuan Zhou, Dan Wu, Yi Zhang

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Dynamic glucose-enhanced MRI in brain tumors.Magma (New York, N.Y.) · 2026
    Review
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  11. Amide proton transfer MRI may reflect effective reperfusion and predict functional outcomes in patients with ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Article
  12. Quantitative Assessment of Peripheral Oxidative Metabolism With a New DynamicJournal of magnetic resonance imaging : JMRI · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ruibin LiuKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Hongxi ZhangDepartment of Radiology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Weiming NiuDepartment of Radiology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Can LaiDepartment of Radiology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Qiuping DingKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Weibo ChenPhilips Healthcare, Shanghai, China.
Sayuan LiangClinical Research Board, Philips Research China, Shanghai, China.
Jinyuan ZhouDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland.
Dan WuKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-9303-5821
Yi ZhangKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0001-8738-1851
Children's Hospital of Zhejiang University · CNJohns Hopkins University · USPhilips (China) · CNZhejiang University · CN

Funding

Academic-Industrial Partnership to Develop Clinical Brain Cancer ImagingR01CA166171 · NCI · JOHNS HOPKINS UNIVERSITY · PI VAN ZIJL, PETER CM, ZHOU, JINYUAN · 2013 to 2017
$2.4M
Amide Proton Transfer (APT) MRI of Brain Tumors at 3TR01CA228188 · NCI · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2019 to 2022
$1.6M
Development of Novel Functional Markers for TBI Using Molecular MRIUH3NS106937 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KOEHLER, RAYMOND CHARLES, ZHOU, JINYUAN · 2020 to 2022
$1.3M
Development of Novel Functional Markers for TBI Using Molecular MRIUG3NS106937 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KOEHLER, RAYMOND CHARLES, ZHOU, JINYUAN · 2018 to 2019
$859k
NCI NIH HHS R01 CA166171NCI NIH HHS R01 CA228188NIH HHS CA166171, CA228188, NS106937NINDS NIH HHS UG3 NS106937NINDS NIH HHS UH3 NS106937
6 · The paper itself

Abstract

purposeTo investigate the effects of frequency drift on chemical exchange saturation transfer (CEST) imaging at 3T, and to propose a new sequence for correcting artifacts attributed to B THEORY AND

methodsA frequency-stabilized CEST (FS-CEST) imaging sequence was proposed by adding a frequency stabilization module to the conventional non-frequency-stabilized CEST (NFS-CEST) sequence, which consisted of a small tip angle radiofrequency excitation pulse and readout of three non-phase-encoded k-space lines. Experiments were performed on an egg white phantom and 26 human subjects on a heavy-duty clinical scanner, in order to compare the difference of FS-CEST and NFS-CEST sequences for generating the z-spectrum, magnetization transfer ratio asymmetry (MTR

resultsThe B

conclusionsThe proposed FS-CEST sequence provides an effective approach for B

Indexed as

Magnetic Resonance ImagingAlgorithmsAnimalsArtifactsChickensChildChild, PreschoolDizzinessEgg WhiteFemaleHeadacheHumansImage Processing, Computer-AssistedMalePhantoms, ImagingRadio Wavesamide proton transfer (APT)chemical exchange saturation transfer (CEST)frequency driftfrequency stabilized CEST (FS-CEST)

Identifiers

PMID30697813
PMCPMC6414244
OpenAlexW2912055843

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.