Evidence map›Paper›PMID 30697693›Full record

ArticleClinical pharmacology and therapeutics2019

Comparison of Different Strategies to Measure Medication Adherence via Claims Data in Patients With Chronic Heart Failure.

Peter Ihle, Katrin Krueger, Ingrid Schubert, Nina Griese-Mammen, Natalie Parrau, Ulrich Laufs, Martin Schulz

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  11. Adherence to Pharmacotherapies After Heart Transplantation in Relation to Multimorbidity and Socioeconomic Position: A Nationwide Register-Based Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter IhlePMV research group, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Katrin KruegerDepartment of Medicine, ABDA - Federal Union of German Associations of Pharmacists, Berlin, Germany.
Ingrid SchubertPMV research group, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Nina Griese-MammenDepartment of Medicine, ABDA - Federal Union of German Associations of Pharmacists, Berlin, Germany.
Natalie ParrauDepartment of Medicine, ABDA - Federal Union of German Associations of Pharmacists, Berlin, Germany.
Ulrich LaufsDepartment of Cardiology, University Hospital, Leipzig University, Leipzig, Germany.
Martin SchulzDepartment of Medicine, ABDA - Federal Union of German Associations of Pharmacists, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication adherence correlates with morbidity and mortality in patients with chronic heart failure (CHF), but is difficult to assess. We conducted a retrospective methodological cohort study in 3,808 CHF patients, calculating adherence as proportion of days covered (PDC) utilizing claims data from 2010 to 2015. We aimed to compare different parameters' influence on the PDC of elderly CHF patients exemplifying a complex chronic disease. Investigated parameters were the assumed prescribed daily dose (PDD), stockpiling, and periods of hospital stay. Thereby, we investigated a new approach using the PDD assigned to different percentiles. The different dose assumptions had the biggest influence on the PDC, with variations from 41.9% to 83.7%. Stockpiling and hospital stays increased the values slightly. These results queries that a reliable PDC can be calculated with an assumed PDD. Hence, results based on an assumed PDD have to be interpreted carefully and should be presented with sensitivity analyses to show the PDC's possible range.

Indexed as

Drug MonitoringAgedAged, 80 and overCardiovascular AgentsDose-Response Relationship, DrugFemaleHeart FailureHumansInsurance Claim ReviewLength of StayMaleResearch DesignRetrospective StudiesSeverity of Illness IndexCardiovascular Agents

Identifiers

PMID30697693
PMCPMC6617982

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.