ArticleCardiology journal2020
Slow breathing improves cardiovascular reactivity to mental stress and health-related quality of life in heart failure patients with reduced ejection fraction.
Article in Cardiology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04307823 (Effects of Respiratory Muscles Training on Cardiopulmonary Parameters and Quality of Life in Patients With Dilated Cardiomyopathy), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Respiratory Muscles Training on Cardiopulmonary Parameters and Quality of Life in Patients With Dilated Cardiomyopathy
Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Neural Mechanisms of Social Homeostasis: Dynamic Range Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- The Rehabilitation Efficacy of the Novel Metronomic Breathing Technique for Gerontic Patients After Percutaneous Coronary Intervention for Acute Myocardial Infarction-A Pilot Study.Clinical interventions in aging · 2024Article
- Existing Meditation and Breathing Devices for Stress Reduction and Their Incorporated Stimuli: A Systematic Literature Review and Competition Analysis.Mayo Clinic proceedings. Digital health · 2023Review
- Induced Relaxation Enhances the Cardiorespiratory Dynamics in COVID-19 Survivors.Entropy (Basel, Switzerland) · 2023Article
- Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization.Health and quality of life outcomes · 2022Article
- Reducing Test Anxiety by Device-Guided Breathing: A Pilot Study.Frontiers in psychology · 2022Article
- The Importance of Respiratory Rate Monitoring: From Healthcare to Sport and Exercise.Sensors (Basel, Switzerland) · 2020Review
- Tachycardia: The hidden cardiovascular risk factor in uncomplicated arterial hypertension.Cardiology journal · 2020Review
- Tai Chi Improves Coronary Heart Disease Risk by Inactivating MAPK/ERK Pathway through Serum miR-126.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Acute effects of resonance frequency breathing on cardiovascular regulation.Physiological reports · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have demonstrated therapeutic benefits of slow breathing (SLOWB) in chronic heart failure (HF) but its impact on cardiovascular reactivity in response to laboratory stressors remains unknown.
methodsUsing device-guided breathing this study explored the acute and long-term effects of SLOWB on hemodynamic responses to handgrip, mental and cold pressor tests, and health-related quality of life (QoL) in stable HF patients with reduced ejection fraction (HFrEF) who had received all available optimal drug and device therapies. Blood pressure (BP) and heart rate (HR) were measured in 21 patients with HFrEF (23.9 ± 5.9%) at rest, during laboratory stressors, before and after acute SLOWB, and 12 weeks after SLOWB home training (30 min daily). Health-related QoL (MacNew questionaries) was assessed before and 12 weeks after SLOWB home training.
resultsResting BP significantly increased in response to three laboratory stressors. Pressor and cardiac changes during mental stress were greater than responses to the handgrip test (p < 0.05). Mental stress also produced a greater HR change than cold pressor test (p < 0.05). Both acute and long-term SLOWB significantly reduced BP and HR responses to mental stress (p < 0.05), but not to isometric and cold pressor tests. SLOWB improved scores of all domains of QoL (p < 0.05) at 12 weeks follow-up.
conclusionsThese findings demonstrate that SLOWB reduces acute and chronic effects of cardiovascular reactivity to mental stress and improves various aspects of health-related QoL in patients with severe HFrEF. Whether stress reduction and psychological changes achieved with SLOWB may translate to improved outcomes in HFrEF warrants further exploration.
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