Evidence map›Paper›PMID 30697575›Full record

ArticleOpen forum infectious diseases2019

Hyperglycemia and Risk of All-cause Mortality Among People Living With HIV With and Without Tuberculosis Disease in Myanmar (2011-2017).

Nang Thu Thu Kyaw, Srinath Satyanarayana, Htun Nyunt Oo, Ajay M V Kumar, Anthony D Harries, Si Thu Aung, Khine Wut Yee Kyaw, Khaing Hnin Phyo, Thet Ko Aung, Matthew J Magee

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Nang Thu Thu KyawCenter for Operational Research, International Union Against Tuberculosis and Lung Disease, The Union Myanmar Office, Mandalay, Myanmar.ORCID 0000-0002-4849-579X
Srinath SatyanarayanaCenter for Operational Research, International Union Against Tuberculosis and Lung Disease, The Union South-East Asia Office, New Delhi, India.
Htun Nyunt OoNational HIV/AIDS Program, Department of Public Health, Nay Pyi Taw, Myanmar.
Ajay M V KumarCenter for Operational Research, International Union Against Tuberculosis and Lung Disease, Paris, France.
Anthony D HarriesCenter for Operational Research, International Union Against Tuberculosis and Lung Disease, Paris, France.
Si Thu AungNational Tuberculosis Program, Department of Public Health, Nay Pyi Taw, Myanmar.
Khine Wut Yee KyawCenter for Operational Research, International Union Against Tuberculosis and Lung Disease, The Union Myanmar Office, Mandalay, Myanmar.
Khaing Hnin PhyoIntegrated HIV Care Program, International Union Against Tuberculosis and Lung Disease, The Union Myanmar Office, Mandalay, Myanmar.
Thet Ko AungIntegrated HIV Care Program, International Union Against Tuberculosis and Lung Disease, The Union Myanmar Office, Mandalay, Myanmar.
Matthew J MageeDivision of Epidemiology and Biostatistics, School of Public Health, Georgia State University, Atlanta, Georgia.
Department of Public Health · MMGeorgia State University · USInternational Union Against Tuberculosis and Lung Disease · FRLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited empirical evidence on the relationship between hyperglycemia, tuberculosis (TB) comorbidity, and mortality in the context of HIV. We assessed whether hyperglycemia at enrollment in HIV care was associated with increased risk of all-cause mortality and whether this relationship was different among patients with and without TB disease.

methodsWe conducted a retrospective analysis of adult (≥15 years) HIV-positive patients enrolled into HIV care between 2011 and 2016 who had random blood glucose (RBG) measurements at enrollment. We used hazards regression to estimate associations between RBG and rate of all-cause mortality.

resultsOf 25 851 patients, 43% were female, and the median age was 36 years. At registration, the median CD4 count (interquartile range [IQR]) was 162 (68-310) cell/mm

conclusionsOur findings highlight an urgent need to evaluate hyperglycemia screening and diagnostic algorithms and to ultimately establish glycemic targets for PLHIV with and without TB disease.

Indexed as

diabetes mellitusloss to follow-upnoncommunicable diseaserestricted cubic splinesensitivity analysis

Identifiers

PMID30697575
PMCPMC6343962
OpenAlexW2907093605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.