Evidence map›Paper›PMID 30697524›Full record

ArticleAvicenna journal of medicine

Possible acute rejection associated with the use of the new anti-hepatitis C virus medications.

Khaled A Karkout, Saleema Al Sherif, Qutaiba Hussein, Alia Albawardi, Yousef Boobes

Abstract readCase Reports
In one paragraph

Article in Avicenna journal of medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khaled A KarkoutDepartment of Internal Medicine, Tawam Hospital, Al-Ain, United Arab Emirates.
Saleema Al SherifDepartment of Internal Medicine, Tawam Hospital, Al-Ain, United Arab Emirates.
Qutaiba HusseinDivision of Nephrology, Tawam Hospital, Al-Ain, United Arab Emirates.
Alia AlbawardiDepartment of Pathology, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates.
Yousef BoobesDivision of Nephrology, Tawam Hospital, Al-Ain, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus infection is associated with increased morbidity and mortality. It remains a major challenge for management and treatment, especially in patients with renal transplant. The new direct-acting antiviral agents gave big hopes to both clinicians and patients that they can overcome this challenge without major side effects. Studies recently have supported this claim; however, they are still few, limited, and may give false hopes. In the following case report, we present a case, supported by histological evidence about a possible acute rejection of kidney transplant after treatment with these new medications. This case is limited by the absence of donor-specific antibodies. This report is aimed to increase awareness about the urgent need for further studies.

Indexed as

Acute rejectionanti-hepatitis C virus medicationdaclatasvirdirect-acting antiviral agentskidney transplantsofosbuvir

Identifiers

PMID30697524
PMCPMC6335885

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.