Evidence map›Paper›PMID 30697460›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2018

Pre-treatment partial-volume-corrected TLG is the best predictor of overall survival in patients with relapsing/refractory non-hodgkin lymphoma following radioimmunotherapy.

Raheleh Taghvaei, Mahdi Zirakchian Zadeh, Reza Sirous, Sara Pourhassan Shamchi, William Y Raynor, Siavash Mehdizadeh Seraj, Mateen Moghbel, Shiyu Wang, Thomas J Werner, Hongming Zhuang and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Predictive Value of CorrectedWorld journal of nuclear medicine · 2024
    Article
  3. Baseline and interimFrontiers in oncology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Correlation of whole-bone marrow dual-time-pointAmerican journal of nuclear medicine and molecular imaging · 2020
    Article
  8. Prognostic significance ofAmerican journal of nuclear medicine and molecular imaging · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Raheleh TaghvaeiDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Mahdi Zirakchian ZadehDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Reza SirousUniversity of Maryland Medical Center Baltimore, MD, USA.
Sara Pourhassan ShamchiDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
William Y RaynorDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Siavash Mehdizadeh SerajDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Mateen MoghbelDepartment of Radiology, Stanford University Medical Center Stanford, CA, USA.
Shiyu WangDepartment of Dermatology, Hospital of The University of Pennsylvania PA, USA.
Thomas J WernerDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Hongming ZhuangDepartment of Radiology, Children's Hospital of Philadelphia PA, USA.
Abass AlaviDepartment of Radiology, Hospital of The University of Pennsylvania PA, USA.
Drexel University · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of fluorodeoxyglucose-positron emission tomography (FDG-PET) has been well established in assessment of lymphoma, including non-Hodgkin lymphoma (NHL). The aim of this study was to compare changes and survival predictive values of various quantification parameters of FDG-PET/CT in patients with relapsing/refractory lymphoma before and after radioimmunotherapy (RIT). Data from 17 patients with relapsing/refractory NHL, treated with targeted RIT after chemotherapy/radiotherapy, were retrospectively collected. FDG-PET/CT scans were performed approximately three months before and six months after RIT. An adaptive contrast-oriented thresholding algorithm was used to segment lesions on the FDG-PET images. Wilcoxon signed-rank tests were used to assess changes in SUVmax, SUVmean, partial volume-corrected SUVmean (pvcSUVmean), total lesion glycolysis (TLG), and pvcTLG before and after treatment. The patients were followed up after completing RIT for up to 10 years. Kaplan-Meier and Cox regression analyses evaluated the association between the quantification parameters and survival data. In the survived group, the decrease in mean percentage of change for TLG and pvcTLG was greater than SUVmax, SUVmean and pvcSUVmean [TLG: 253.9 to 106.9, -81.4%;

Indexed as

FDGglobal disease assessmentpartial volume correctionPositron emission tomographyradioimmunotherapyrelapsing/refractory non-hodgkin lymphoma

Identifiers

PMID30697460
PMCPMC6334213
OpenAlexW2997171527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.