ReviewWorld journal of gastrointestinal pharmacology and therapeutics2019
Update on the management of gastrointestinal varices.
Review in World journal of gastrointestinal pharmacology and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of EUS-Guided Coil Embolization Combined With Endoscopic Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration for Gastric Varices With High-risk Ectopic Embolism
Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy for the Control of Acute Variceal Bleeding in Patients With Liver Cirrhosis at a Tertiary Center in Mexico
Endoscopic Ultrasound-guided Coil With Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration in Managing Patients With Gastric Varices
Accuracy of Simple Objective Scores in Prediction of Short-Term Outcome Among Cirrhotic Patients With Variceal Bleeding
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- The Efficacy and Safety of Clip-Assisted Endoscopic Cyanoacrylate Injection for Gastric Varices: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2026Pooled it
- Use of single-use ultra-slim endoscopes for evaluation of pediatric esophageal varices: A pilot feasibility study.JPGN reports · 2026Article
- Predicting esophageal varices in cirrhosis: diagnostic utility of MR elastography and dynamic contrast-enhanced MRI.Abdominal radiology (New York) · 2026Article
- Association of pre-endoscopic fresh frozen plasma transfusion with clinical outcomes in patients with acute upper gastrointestinal bleeding and mild coagulopathy: a two-center retrospective cohort study.Scientific reports · 2026Article
- Endoscopic urgency triaging impacts acute variceal bleeding patient survival and hospital stay length.The Libyan journal of medicine · 2025Article
- Computed tomography poorly detects gastroesophageal varices compared with endoscopy: a real-world single-center retrospective review.BMC gastroenterology · 2025Article
- Use of wireless capsule endoscopy for the diagnosis and grading of esophageal varices in patients with portal hypertension: A systematic review and meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- Article
- Article
- Risk Factors for Glue Extrusion Bleeding After Endoscopic Injection of Cyanoacrylate Glue for Gastric Varices: A Retrospective Study of 269 Patients.Digestive diseases and sciences · 2025Article
- Endoscopic ultrasound-guided treatment of isolated gastric varices.World journal of gastrointestinal endoscopy · 2025Article
- Screening for exclusion of high-risk bleeding features of esophageal varices in cirrhosis through CT and MRI.Clinical imaging · 2024Article
- Reinforcing the management of type 1 gastric esophageal varices.World journal of gastroenterology · 2024Article
- Thrombocytopenia and Grading of Esophageal Varices in Patients With Chronic Liver Disease.Cureus · 2024Article
- The Prediction and Treatment of Bleeding Esophageal Varices in the Artificial Intelligence Era: A Review.Cureus · 2024Review
- Endoscopic management of bleeding ectopic varices: multicentric retrospective case series.Przeglad gastroenterologiczny · 2024Article
- A Fatal Retroperitoneal Hematoma From a Massive Mesenteric Variceal Bleeding.ACG case reports journal · 2023Article
- Hepatic Venous Pressure Gradient Predicts Further Decompensation in Cirrhosis Patients with Acute Esophageal Variceal Bleeding.Diagnostics (Basel, Switzerland) · 2023Article
- Acute-on-chronic liver failure is independently associated with higher mortality for cirrhotic patients with acute esophageal variceal hemorrhage: Retrospective cohort study.World journal of clinical cases · 2023Article
- [Lesions of the paravertebral mediastinum].Radiologie (Heidelberg, Germany) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cirrhosis of liver is a major problem in the western world. Portal hypertension is a complication of cirrhosis and can lead to a myriad of pathology of which include the development of porto-systemic collaterals. Gastrointestinal varices are dilated submucosal veins, which often develop at sites near the formation of gastroesophageal collateral circulation. The incidence of varices is on the rise due to alcohol and obesity. The most significant complication of portal hypertension is life-threatening bleeding from gastrointestinal varices, which is associated with substantial morbidity and mortality. In addition, this can cause a significant burden on the health care facility. Gastrointestinal varices can happen in esophagus, stomach or ectopic varices. There has been considerable progress made in the understanding of the natural history, pathophysiology and etiology of portal hypertension. Despite the development of endoscopic and medical treatments, early mortality due to variceal bleeding remains high due to significant illness of the patient. Recurrent variceal bleed is common and in some cases, there is refractory variceal bleed. This article aims to provide a comprehensive review of the management of gastrointestinal varices with an emphasis on endoscopic interventions, strategies to handle refractory variceal bleed and newer endoscopic treatment modalities. Early treatment and improved endoscopic techniques can help in improving morbidity and mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.