ReviewJournal of clinical and experimental dentistry2019
Actinic cheilitis and lip squamous cell carcinoma: Literature review and new data from Brazil.
Review in Journal of clinical and experimental dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Clinicopathological Analysis of Actinic Cheilitis: A Systematic Review with Meta-analyses.Head and neck pathology · 2023Pooled it
- Actinic cheilitis and associated factors in fishermen living in a rural riverside community in the Amazon.Brazilian dental journal · 2025Article
- Decreased Nuclear Immunoexpression of ING3 is a Frequent Event in Lip Carcinogenesis.Head and neck pathology · 2024Article
- Squamous cell carcinoma and basal cell carcinoma of the lips: 25 years of experience in a northeast Brazilian population.Medicina oral, patologia oral y cirugia bucal · 2024Article
- Evaluation of lip diseases in peddlers on two beaches of Guarujá/Brazil: An observational study.Brazilian dental journal · 2024Observational
- Actinic cheilitis: Proposal of a clinical index.Medicina oral, patologia oral y cirugia bucal · 2022Article
- Lip Reconstruction by Double Layer and Double Flap New Combination Technique: A Case Series.Dentistry journal · 2022Article
- Identification of Prognostic Markers of N6-Methylandenosine-Related Noncoding RNAs in Non-Small-Cell Lung Cancer.Journal of oncology · 2022Article
- Immunoexpression of PD-L1, CD4+ and CD8+ cell infiltrates and tumor-infiltrating lymphocytes (TILs) in the microenvironment of actinic cheilitis and lower lip squamous cell carcinoma.Journal of applied oral science : revista FOB · 2022Article
- Telemedicine contributing to an incidental finding of a premalignant lesion.Oral oncology · 2021Article
- Epithelial Dysplasia in Actinic Cheilitis: Microscopic Study of 70 Cases from Brazil.Head and neck pathology · 2021Article
- Demographic and Clinicopathologic Features of Actinic Cheilitis and Lip Squamous Cell Carcinoma: a Brazilian Multicentre Study.Head and neck pathology · 2020Article
- Epidemiology and pathological progression of erythematous lip lesions in captive sun bears (Helarctos malayanus).PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the prevalence of malignant and potentially malignant lesions of the lip in an oral pathology service and to compare these data with a literature review. MATERIAL AND
methodsA total of 3173 biopsy reports and histopathological records were analyzed. Cases with a histological diagnosis of actinic cheilitis (AC) with or without epithelial dysplasia, in situ carcinoma, or lip squamous cell carcinoma (LSCC) were included. A comprehensive literature review was conducted to investigate the prevalence of AC and/or LSCC.
results124 cases (3.91%) were included, 75 (60.5%) had some degree of epithelial dysplasia and 31 (25.0%) were LSCC. Clinically, most of the lesions were diagnosed as AC (50.8%); however, eight cases clinically reported as AC were histologically diagnosed as LSCC. Regarding clinical characteristics, most individuals were fair-skinned male, with mean age of 54.3±12.3 years, and with a history of long-term solar exposure. Furthermore, 18 articles were selected from the literature, showing that the lower lip was predominantly affected and that most individuals were males, fair-skinned, and older than 40 years.
conclusionsSince most of the cases diagnosed clinically as AC presented some degree of epithelial dysplasia, it is important to emphasize the value of biopsy and the histological evaluation of this lesion.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.