ArticleWorld journal of diabetes2019
Relationship between sonographically measured median nerve cross-sectional area and presence of peripheral neuropathy in diabetic subjects.
Article in World journal of diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Clinical value of high-frequency ultrasound and serum miR-92a-3p in diabetic peripheral neuropathy.Journal of diabetes investigation · 2025Article
- Nerve ultrasound helps to distinguish CIDP patients with diabetes from patients with diabetic polyneuropathy.Scientific reports · 2024Article
- Diabetes Increases Median Nerve Cross-Sectional Area but Not Disease Severity in Patients with Carpal Tunnel Syndrome.Journal of hand and microsurgery · 2024Article
- Nerve ultrasonographic findings in diabetes mellitus are determined by anatomical location and type of diabetes.Clinical neurophysiology practice · 2023Article
- Electrodiagnostic Testing and Nerve Ultrasound of the Carpal Tunnel in Patients with Type 2 Diabetes.Journal of clinical medicine · 2022Article
- Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- High resolution ultrasonography of peripheral nerves in diabetic patients to evaluate nerve cross sectional area with clinical profile.The British journal of radiology · 2021Observational
- Lumos for the long trail: Strategies for clinical diagnosis and severity staging for diabetic polyneuropathy and future directions.Journal of diabetes investigation · 2020Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuropathy is a common complication of diabetes mellitus resulting from direct damage by hyperglycemia to the nerves and/or ischemia by microvascular injury to the endoneurial vessels which supply the nerves. Median nerve is one of the peripheral nerves commonly affected in diabetic neuropathy. The median nerve size has been studied in non-Nigerian diabetic populations. In attempt to contribute to existing literature, a study in a Nigerian population is needed.
aimTo evaluate the cross-sectional area (CSA) of the median nerve using B-mode ultrasonography (USS) and the presence of peripheral neuropathy (PN) in a cohort of adult diabetic Nigerians.
methodsDemographic and anthropometric data of 85 adult diabetes mellitus (DM) and 85 age- and sex-matched apparently healthy control (HC) subjects were taken. A complete physical examination was performed on all study subjects to determine the presence of PN and modified Michigan Neuropathy Screening Instrument (MNSI) was used to grade its severity. Venous blood was taken from the study subjects for fasting lipid profile (FLP), fasting blood glucose (FBG) and glycated haemoglobin (HbA1c) while their MN CSA was evaluated at a point 5 cm proximal to (5cmCATL) and at the carpal tunnel (CATL) by high-resolution B-mode USS. Data was analysed using SPSS version 22.
resultsThe mean MN CSA was significantly thicker in DM subjects compared to the HC at 5cmCATL (
conclusionThickening of the MN CSA at 5cmCATL and CATL is seen in DM. Presence of DPN is associated with worse thickening of the MN CSA at the CATL but not at 5cmCATL. Severity of DPN, duration of DM, and glycemic control had no additional effect on the MN CSA.
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