Evidence map›Paper›PMID 30697307›Full record

ArticleIranian journal of parasitology

Identification of Clinical Immunological Determinants in Asymptomatic VL and Post Kala-azar Dermal Leishmaniasis Patients.

Ashish Kumar Singh, Vidya Nand Rabi DAS, Ajay Amit, Manas R Dikhit, Vijaya Mahantesh, Akhilesh Kumar, Raj Kishore Pandey, Shyam Naryan, Bipin K Singh, Krishna Pandey and 3 more

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Biomarkers in Post-kala-azar Dermal Leishmaniasis.Frontiers in cellular and infection microbiology · 2019
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Ashish Kumar SinghDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Vidya Nand Rabi DASDept. of Pathology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Ajay AmitDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Manas R DikhitDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Vijaya MahanteshDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Akhilesh KumarDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Raj Kishore PandeyDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Shyam NaryanDept. of Microbiology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Bipin K SinghDept. of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Krishna PandeyDept. of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Neena VermaDept. of Pathology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Pradeep DASDept. of Molecular Biology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Sanjiva BimalDept. of Immunology, Rajendra Memorial Research Institute of Medical Sciences, Patna, India.
Rajendra Memorial Research Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisceral Leishmaniasis (VL) caused by protozoa belonging to the genus

methodsEighty-four participants were included at RMRIMS, Patna, India in 2016-17 out of which 64 asymptomatic individual positive for rK-39, without sign and symptoms of VL; 15 PKDL patient's with past history of VL and 5 endemic healthy subjects were recruited from VL endemic areas. DAT and quantitative assessment of plasma cytokines was determined from the blood samples collected in a plain and sodium-EDTA vacutainer respectively from the subjects.

resultsThe mean level of IL-10 in DAT

conclusionCollectively we surmise from our data that asymptomatic VL can also play an important role like PKDL in transmission of VL.

Indexed as

Asymptomatic infectionCytokineDirect agglutination testIFN-gammaInterleukin-10Tumor necrosis factor-alphaVisceral leishmaniasis

Identifiers

PMID30697307
PMCPMC6348209
OpenAlexW2914879137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.