Evidence map›Paper›PMID 30697217›Full record

ReviewFrontiers in immunology2018

Dietary Habits and Intestinal Immunity: From Food Intake to CD4

Francesco Siracusa, Nicola Schaltenberg, Eduardo J Villablanca, Samuel Huber, Nicola Gagliani

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05779449 (Targeting the Gut Dysbiosis to Treat Inflammation-driven Synaptopathy in Multiple Sclerosis), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05779449 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Targeting the Gut Dysbiosis to Treat Inflammation-driven Synaptopathy in Multiple Sclerosis

TypeinterventionalSponsorNeuromed IRCCSRan2023 to 2026Enrolled100ConditionsPatient ParticipationArmsPrebiotics and Probiotics supplementation, Placebo supplementation, peripheral blood withdrawal, Transcranial Magnetic Stimulation (TMS)
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 87 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Francesco SiracusaDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nicola SchaltenbergDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Eduardo J VillablancaImmunology and Allergy Unit, Department of Medicine Solna, Karolinska Institute and University Hospital, Stockholm, Sweden.
Samuel HuberDepartment of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nicola GaglianiDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
University Medical Center Hamburg-Eppendorf · DEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary habits have a profound impact on intestinal homeostasis and in general on human health. In Western countries, high intake of calories derived from fried products, butter and processed meat is favored over dietary regimens rich in fruits and vegetables. This type of diet is usually referred to as Western-type diet (WTD) and it has been associated with several metabolic and chronic inflammatory conditions of the gastrointestinal tract. In this review, we describe how WTD promotes intestinal and extra-intestinal inflammation and alters mucosal immunity acting on CD4

Indexed as

Feeding BehaviorAnimalsEatingEnterocolitisGastrointestinal MicrobiomeHumansImmune SystemImmunity, MucosalIntestinesT-Lymphocytes, Helper-InducerCD4 T cellsfatfiberinflammationmicrobiotamucosal immunitysaltwestern diet

Identifiers

PMID30697217
PMCPMC6340974
OpenAlexW2910844538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.