Evidence map›Paper›PMID 30697066›Full record

ArticleCancer management and research2019

Comparative study of adjuvant chemotherapeutic efficacy of docetaxel plus cyclophosphamide and doxorubicin plus cyclophosphamide in female breast cancer.

Muhammad Adeel, Muhammad Asif, Muhammad Naeem Faisal, Muhammad Hasanain Chaudary, Muhammad Sheraz Malik, Muhammad Khalid

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Muhammad AdeelDepartment of Computer Science, Faculty of Science, National Textile University, Faisalabad, Punjab, Pakistan, asif@ntu.edu.pk.
Muhammad AsifDepartment of Computer Science, Faculty of Science, National Textile University, Faisalabad, Punjab, Pakistan, asif@ntu.edu.pk.
Muhammad Naeem FaisalFaculty of Veterinary Science, Institute of Pharmacy, Physiology, and Pharmacology, University of Agriculture, Faisalabad, Punjab, Pakistan.
Muhammad Hasanain ChaudaryDepartment of Computer Science, COMSATS University, Islamabad, Lahore Campus, Lahore, Punjab, Pakistan.
Muhammad Sheraz MalikDepartment of Information Technology, Government College University, Faisalabad, Punjab, Pakistan.
Muhammad KhalidOncology Department, Faisalabad Medical University, Allied Hospital, Faisalabad, Punjab, Pakistan.
National Textile University · PKCOMSATS University Islamabad · PKGovernment College University, Faisalabad · PKPunjab Medical College · PKUniversity of Agriculture Faisalabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis retrospective study presents a comparative analysis of the overall survival and toxicities, as side effects, of docetaxel plus cyclophosphamide (TC) and doxorubicin plus cyclophosphamide (AC). The study measured their efficacies during adjuvant chemotherapy, treating Pakistani breast cancer patients by validating the results obtained, with the published analysis of the same treatment given to US patients. PATIENTS AND

methodsBetween June 2015 and September 2017, for four chemotherapy cycles, 189 patients out of 358 received TC (75 mg/m

resultsThere was no statistically significant difference between the proportions of patients with vomiting, extreme tiredness, diarrhea, mild anemia, stability, and overall survival because

conclusionAt 27 months, TC was more toxic than AC, whereas both combinations had the same overall survival rate.

Indexed as

overall survivalpathological markerspatient health during chemotherapyTC vs ACtoxicity of anticancer drugs

Identifiers

PMID30697066
PMCPMC6339652
OpenAlexW2909817324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.