Evidence map›Paper›PMID 30697038›Full record

ArticlePatient preference and adherence2019

Multicenter study of patients' preferences and concerns regarding the origin of bone grafts utilized in dentistry.

Cristina Bucchi, Massimo Del Fabbro, Alain Arias, Ramón Fuentes, José Manuel Mendes, Marie Ordonneau, Valérie Orti, María-Cristina Manzanares-Céspedes

Abstract read
In one paragraph

Article in Patient preference and adherence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Bone Grafts: Everything You Need to Know.Journal of periodontal research · 2026
    Review
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  8. Article
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  12. Article
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  14. Article
  15. Patients' Perspectives of Grafting Materials in Implant Dentistry: A Qualitative Analysis.Journal of International Society of Preventive & Community Dentistry
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristina BucchiPhD Program in Medicine and Translational Research, Universitat de Barcelona, Barcelona, Spain, cristina.bucchi@ufrontera.cl.
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy.
Alain AriasDepartment of Integral Adults Dentistry, Research Centre for Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile, cristina.bucchi@ufrontera.cl.
Ramón FuentesDepartment of Integral Adults Dentistry, Research Centre for Dental Sciences (CICO), Dental School, Universidad de La Frontera, Temuco, Chile, cristina.bucchi@ufrontera.cl.
José Manuel MendesCESPU, IINFACTS, Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Dental Sciences, Portugal.
Marie OrdonneauFaculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.
Valérie OrtiDepartment of Periodontology, Dental School, University of Montpellier, Montpellier, France.
María-Cristina Manzanares-CéspedesFaculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBone graft materials can be obtained from the patient's own body (autologous graft), animals (xenograft), human cadavers (allograft) and synthetic materials (alloplastic bone graft). Patients may have ethical, religious or medical concerns about the origin of bone grafts, which could lead them to reject the use of certain types of bone graft in their treatments. The aim of this multicenter study, which surveyed patients from five university clinics in Portugal, France, Italy, Spain and Chile, was to analyze patients' opinions regarding the source of bone grafts. PATIENTS AND

methodsA survey composed of ten questions was translated into local languages and validated. Patients were asked about the degree of acceptance/rejection of each graft and the reasons for rejection. A chi-squared test was used to analyze statistically significant differences.

resultsThree hundred thirty patients were surveyed. The grafts that elicited the highest percentage of refusal were allograft (40.4%), autologous bone graft from an extraoral donor site (34%) and xenograft (32.7%). The grafts with the lowest rate of refusal were alloplastic (6.3%) and autologous bone grafts from an intraoral donor site (24.5%). The main reason for autologous bone rejection was the fear of pain and discomfort, for xenograft it was the fear of disease transmission and the rejection of use of animals for human benefit, and for allograft it was ethical/moral motivations and the fear of disease transmission. Religious affiliation influenced patient's preferences.

conclusionThe origin of bone grafts is still conflictive for a high percentage of patients.

Indexed as

animal productsbone graft materialspatient’s concernssurveytissue donation

Identifiers

PMID30697038
PMCPMC6342143

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.