ArticlePediatric research2019
The point-of-care Bilistick method has very short turn-around-time and high accuracy at lower cutoff levels to predict laboratory-measured TSB.
Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Predictive value of the 24-hour bilirubin in the development of significant hyperbilirubinemia among Filipino term (≥37 weeks gestational age) infants: a prospective multi-center study.Pediatric research · 2026Article
- Diagnostic performance of point-of-care bilirubin testing with Bilistick 2.0 device at a South Indian clinical site.Pediatric research · 2026Article
- Point-of-care serum bilirubin as an efficient and comparable alternative to hospital based testing.Pediatric research · 2026Article
- Assessing Diagnostic Accuracy of a Handheld Point-of-Care Device for Quantifying Neonatal Bilirubin Levels: The BEAT Jaundice @Home Study.Neonatology · 2026Article
- [Global disease burden of neonatal jaundice from 1990 to 2019].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- 175 Years of Bilirubin Testing: Ready for Point-of-Care?Advanced healthcare materials · 2023Article
- Observational
- Diagnostic methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments.Pediatric research · 2021Review
- Commentary on "The point-of-care Bilistick method has very short turn-around-time and high accuracy at lower cut-off levels to predict laboratory-measured TSB."Pediatric research · 2019Article
- Clinicopathological Spectrum of Bilirubin Encephalopathy/Kernicterus.Diagnostics (Basel, Switzerland) · 2019Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to determine the accuracy of a point-of-care Bilistick method for measuring total serum bilirubin (TSB) and its turn-around-time (TAT) against hospital laboratory methods.
methodsThis prospective study was carried out on 561 term-gestation jaundiced neonates in two Malaysian hospitals. Venous blood sample was collected from each neonate for contemporary measurement of TSB by hospital laboratories and Bilistick. TAT was the time interval between specimen collection and TSB result reported by each method.
resultsThe mean laboratory-measured TSB was 194.85 (±2.844) µmol/L and Bilistick TSB was 169.37 (±2.706) µmol/L. Pearson's correlation coefficient was: r = 0.901 (p < 0.001). The mean difference of [laboratory TSB- Bilistick TBS] was 26.48 (±29.41) µmol/L. The Bland-Altman plots show that the 95% limits of agreement (-31.1577, 84.11772) contain 94.7% (=531/561) of the difference in TSB readings. Bilistick has a 99% accuracy and 100% sensitivity to predict laboratory TSB levels of ≥80 µmol/L and ≥360 µmol/L at lower Bilistick TSB levels of ≥55 and ≥315 µmol/L, respectively. TAT of Bilistick TSB (2.0 min) was significantly shorter than TAT (105 min) of laboratory TSB (p < 0.001).
conclusionsBilistick has shorter TAT. The accuracy and sensitivity of Bilistick TSB for predicting laboratory TSB is high at lower cutoff levels.
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