ArticleThe Journal of biological chemistry2019
Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport.
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Review
- Noncanonical RGS14 structural determinants control hormone-sensitive NPT2A-mediated phosphate transport.The Biochemical journal · 2025Article
- The Molecular Biology of Placental Transport of Calcium to the Human Foetus.International journal of molecular sciences · 2025Review
- The Intricacies of Renal Phosphate Reabsorption-An Overview.International journal of molecular sciences · 2024Review
- The molecular sociology of NHERF1 PDZ proteins controlling renal hormone-regulated phosphate transport.Bioscience reports · 2024Article
- Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia.The Biochemical journal · 2023Article
- The Identification of Immune-Related Biomarkers for Osteoarthritis Immunotherapy Based on Single-Cell RNA Sequencing Analysis.Genetics research · 2023Article
- Transmembrane protein 88 suppresses hepatocellular carcinoma progression and serves as a novel prognostic factor.Frontiers in oncology · 2023Article
- The Clinical and Cellular Impact of RBMS2 on the Progression and Prognosis of Kidney Renal Clear Cell Carcinoma.Genetics research · 2023Article
- RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein.The Journal of biological chemistry · 2022Article
- Functional role and regulation of permeability-glycoprotein (P-gp) in the fetal membrane during drug transportation.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022Article
- Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker.Disease markers · 2022Article
- Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis.Genetics research · 2022Article
- Review
- Noncanonical Sequences Involving NHERF1 Interaction with NPT2A Govern Hormone-Regulated Phosphate Transport: Binding Outside the Box.International journal of molecular sciences · 2021Review
- Dynamic structure of the full-length scaffolding protein NHERF1 influences signaling complex assembly.The Journal of biological chemistry · 2019Article
- Parallel Post-Translational Modification Scanning Enhancing Hydrogen-Deuterium Exchange-Mass Spectrometry Coverage of Key Structural Regions.Analytical chemistry · 2019Article
- Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport.The Journal of biological chemistryArticle
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 3 countries.
Qiangmin ZhangFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
Kunhong XiaoFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
José M Paredesthe Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, 18071-Granada, Spain.
Tatyana MamonovaFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
W Bruce SneddonFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
Hongda LiuFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
Dawei WangFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
Sheng Lithe Department of Medicine, University of California San Diego, La Jolla, California 92093, and.
Jennifer C McGarveyFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.
David Uehlingthe Department of Drug Discovery, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Rima Al-Awarthe Department of Drug Discovery, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Babu Josephthe Department of Drug Discovery, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.
Frederic Jean-AlphonseFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology.ORCID 0000-0002-7380-5825
Angel Ortethe Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, 18071-Granada, Spain.
Peter A FriedmanFrom the Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, paf10@pitt.edu.ORCID 0000-0003-1905-1468
University of Pittsburgh · USOntario Institute for Cancer Research · CAUniversidad de Granada · ESUniversity of California San Diego · US
Funding
Hormonal Regulation of NHERF1 in BoneR01DK105811 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, PETER A · 2016 to 2019
$2.5MFunctional Polarity of PTH Receptor Signaling: Cellular and Molecular MechanismsR01DK111427 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, PETER A, VILARDAGA, JEAN-PIERRE · 2017 to 2020
$2.4MRegulation of Parathyroid Functions By G-Protein Coupled ReceptorsR01DK122259 · NIDDK · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI CHANG, WENHAN, VILARDAGA, JEAN-PIERRE · 2019 to 2023
$2.2MNIDDK NIH HHS R01 DK105811NIDDK NIH HHS R01 DK111427NIDDK NIH HHS R01 DK122259
Abstract
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Indexed as
Amino Acid SequenceCrystallography, X-RayFuransHEK293 CellsHumansIon TransportLipidsParathyroid HormonePhosphatesPhosphoproteinsPhosphorylationProtein ConformationReceptors, Neuropeptide YSerineSodium-Hydrogen ExchangersSodium-Phosphate Cotransporter Proteins, Type IIaFuransLipidsneuropeptide Y4 receptorParathyroid HormonePhosphatesPhosphoproteinsReceptors, Neuropeptide YSerineSLC34A1 protein, humansodium-hydrogen exchanger regulatory factorSodium-Hydrogen ExchangersSodium-Phosphate Cotransporter Proteins, Type IIatautomycetinhydrogen–deuterium exchangeNHERF1NPT2APDZ domainphosphate transportphosphoprotein phosphatase 1 (PP1)protein phosphorylationprotein–protein interactionstructural biology
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.