Evidence map›Paper›PMID 30696769›Full record

ArticleThe Journal of biological chemistry2019

Identification of novel autoinducer-2 receptors in

Inês M Torcato, Meghann R Kasal, Patrícia H Brito, Stephen T Miller, Karina B Xavier

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 48 citations in OpenAlex.

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  16. An Efficient Synthesis of Optically Active [4-Molecules (Basel, Switzerland) · 2021
    Article
  17. The role of solute binding proteins in signal transduction.Computational and structural biotechnology journal · 2021
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Inês M TorcatoFrom the Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.ORCID 0000-0001-8311-1096
Meghann R Kasalthe Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, Pennsylvania 19081, and.
Patrícia H BritoFrom the Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.
Stephen T Millerthe Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, Pennsylvania 19081, and smiller1@swarthmore.edu.ORCID 0000-0003-2207-7159
Karina B XavierFrom the Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal, kxavier@igc.gulbenkian.pt.ORCID 0000-0001-5210-1434
Instituto Gulbenkian de Ciência · PTSwarthmore College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoinducer-2 (AI-2) is unique among quorum-sensing signaling molecules, as it is produced and recognized by a wide variety of bacteria and thus facilitates interspecies communication. To date, two classes of AI-2 receptors have been identified: the LuxP-type, present in the

Indexed as

Amino Acid SubstitutionBacterial ProteinsBinding SitesCalorimetryClostridiumCrystallography, X-RayEndocytosisHomoserineLactonesMembrane ProteinsMicrobiotaPhylogenyProtein BindingProtein ConformationQuorum SensingSignal TransductionBacterial ProteinsHomoserineLactonesMembrane ProteinsN-octanoylhomoserine lactoneABC transportersautoinducer-2cell signalingClostridium autoethanogenumClostridium saccharobutylicumcrystal structureisothermal titration calorimetry (ITC)LsrB receptorsmicrobiomequorum sensing

Identifiers

PMID30696769
PMCPMC6433074
OpenAlexW2914292693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.