ArticlemBio2019
Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.
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Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- The multiple roles of the NlpC_P60 peptidase family in mycobacteria - an underexplored target for antimicrobial drug discovery.FEBS letters · 2025Review
- Modulation of the lytic apparatus by the FtsEX complex within the bacterial division machinery.FEBS letters · 2024Review
- In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe.Journal of the American Chemical Society · 2024Article
- Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell ofProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis.Nature communications · 2023Article
- DipM controls multiple autolysins and mediates a regulatory feedback loop promoting cell constriction in Caulobacter crescentus.Nature communications · 2023Article
- Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions.Cell chemical biology · 2023Review
- FtsEX-independent control of RipA-mediated cell separation inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid-shaped cells of Streptococcus pneumoniae D39.Molecular microbiology · 2022Article
- Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.PLoS pathogens · 2022Article
- Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division of Streptococcus pneumoniae.Molecular microbiology · 2021Article
- Article
- Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.Chemical reviews · 2021Review
- The Pneumococcal Divisome: Dynamic Control ofFrontiers in microbiology · 2021Review
- Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Article
- Uncovering the activities, biological roles, and regulation of bacterial cell wall hydrolases and tailoring enzymes.The Journal of biological chemistry · 2020Review
- Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan.Nature microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 3 countries.
Britta E Rued *Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.
Martín Alcorlo *Department of Crystallography and Structural Biology, Instituto Química-Física Rocasolano, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Katherine A EdmondsDepartment of Chemistry, Indiana University Bloomington, Bloomington, Indiana, USA.
Siseth Martínez-CaballeroDepartment of Crystallography and Structural Biology, Instituto Química-Física Rocasolano, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Daniel StraumeDepartment of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Yue FuDepartment of Chemistry, Indiana University Bloomington, Bloomington, Indiana, USA.
Kevin E BruceDepartment of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.
Hongwei WuDepartment of Chemistry, Indiana University Bloomington, Bloomington, Indiana, USA.
Leiv S HåvarsteinDepartment of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Juan A HermosoDepartment of Crystallography and Structural Biology, Instituto Química-Física Rocasolano, Consejo Superior de Investigaciones Científicas, Madrid, Spain xjuan@iqfr.csic.es winklerm@indiana.edu giedroc@indiana.edu.
Malcolm E WinklerDepartment of Biology, Indiana University Bloomington, Bloomington, Indiana, USA xjuan@iqfr.csic.es winklerm@indiana.edu giedroc@indiana.edu.
David P GiedrocDepartment of Chemistry, Indiana University Bloomington, Bloomington, Indiana, USA xjuan@iqfr.csic.es winklerm@indiana.edu giedroc@indiana.edu.ORCID 0000-0002-2342-1620
Indiana University Bloomington · USConsejo Superior de Investigaciones Científicas · ESNorwegian University of Life Sciences · NO
Funding
Transition Metal Homeostasis and Reactive Sulfur Species in Bacterial PathogensR35GM118157 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI DAVID P. GIEDROC · 2016 to 2026
$5.9MNew Regulatory Interactions and Circuits that Mediate the Dynamics, Homeostasis, and Stress Responses of Peptidoglycan Synthesis in the Superbug Streptococcus pneumoniaeR35GM131767 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI MALCOLM E. WINKLER · 2019 to 2026
$4.8MMechanisms of Chemokine Killing and Resistance of Streptococcus pneumoniaeR01GM114315 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WINKLER, MALCOLM E. · 2015 to 2018
$1.1MGraduate Program in Quantitative and Chemical Biology at Indiana University BloomT32GM109825 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GIEDROC, DAVID P. · 2014 to 2018
$926kNew Regulatory Circuits that Mediate Peptidoglycan Homeostasis and Cell Wall Stress Responses in the Superbug Streptococcus pneumoniaeR01GM127715 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WINKLER, MALCOLM E. · 2018 to 2019
$630kNIGMS NIH HHS R01 GM114315NIGMS NIH HHS R01 GM127715NIGMS NIH HHS R35 GM118157NIGMS NIH HHS R35 GM131767NIGMS NIH HHS T32 GM109825
Abstract
PubMed holds no abstract for this paper.
Indexed as
Bacterial ProteinsCell Cycle ProteinsCrystallography, X-RayDNA Mutational AnalysisGenes, EssentialMagnetic Resonance SpectroscopyMicrobial ViabilityModels, MolecularN-Acetylmuramoyl-L-alanine AmidaseProtein BindingProtein ConformationStreptococcus pneumoniaeBacterial ProteinsCell Cycle ProteinsFtsX protein, bacteriaN-Acetylmuramoyl-L-alanine AmidasePcsB protein, Streptococcus pneumoniaecell divisionNMR structurepeptidoglycan hydrolasesprotein-protein interactionsStreptococcus pneumoniae
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.