Evidence map›Paper›PMID 30696717›Full record

ArticleGenetics2019

Sequence Characteristics Distinguish Transcribed Enhancers from Promoters and Predict Their Breadth of Activity.

Laura L Colbran, Ling Chen, John A Capra

Open access · hybridAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura L ColbranVanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee 37235.ORCID 0000-0002-7752-6671
Ling ChenDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235.
John A CapraVanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee 37235 tony.capra@vanderbilt.edu.ORCID 0000-0001-9743-1795
Vanderbilt University · US

Funding

The Evolution of Gene Regulation and Human DiseaseR35GM127087 · NIGMS · VANDERBILT UNIVERSITY · PI John Anthony Capra · 2018 to 2026
$3.2M
Training Program on Genetic Variation and Human PhenotypesT32GM080178 · NIGMS · VANDERBILT UNIVERSITY · PI COX, NANCY J, SAMUELS, DAVID C · 2007 to 2021
$3.1M
Modeling the Dynamics of Genome-Scale Data Across TreesR01GM115836 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAPRA, JOHN ANTHONY, KOSTKA, DENNIS · 2015 to 2017
$1.1M
NIGMS NIH HHS R01 GM115836NIGMS NIH HHS R35 GM127087NIGMS NIH HHS T32 GM080178
6 · The paper itself

Abstract

Enhancers and promoters both regulate gene expression by recruiting transcription factors (TFs); however, the degree to which enhancer

Indexed as

Base CompositionEnhancer Elements, GeneticModels, GeneticPromoter Regions, GeneticHistone CodeHumansSupport Vector MachineTranscriptional ActivationTranscription FactorsTranscription Factorsenhancersgene regulationmachine learningpromoterssequence analysis

Identifiers

PMID30696717
PMCPMC6456323
OpenAlexW2914108095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.