ArticleMicrobiome2019
Enterobacteriaceae dominate the core microbiome and contribute to the resistome of arugula (Eruca sativa Mill.).
Article in Microbiome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed.
- Daidai Flower Essential Oil as a Multifunctional Natural Agent: Chemical Profile, Antimicrobial Activity, Preliminary Insecticidal Potential, and Improved Microbiological Quality of Fresh Arugula During Refrigerated Storage.Journal of food science · 2026Article
- From Traditional to Omics-Driven: Emerging Strategies for Isolation, Cultivation, and Identification of Plant Endophytes.Plants (Basel, Switzerland) · 2026Review
- Phenotypic resistance profiles and resistome variations between endophytic and epiphytic bacteria in apple fruits.Environmental microbiome · 2026Article
- Effects of Inorganic Fluoride and the Fluoroquinolone Antibiotic Pefloxacin on the Growth and Microbiome Structure ofInternational journal of molecular sciences · 2026Article
- Article
- Translational microbiomes in agriculture: microbial communities as tools to effect host and system health for improved crop production.Applied and environmental microbiology · 2026Review
- Diversity and selected functional traits of microbiota associated with traditional dried plant foods from South African informal markets.FEMS microbes · 2026Article
- Linking the edible plant microbiome and human gut microbiome.Gut microbes · 2025Review
- Hotspots of Bacterial Pathogen Abundance and Exposure Risk in Soils of the Contiguous United States.GeoHealth · 2025Article
- Genetic diversity, virulence factors and drug resistance ofJournal of veterinary research · 2025Article
- Shotgun Metagenome Analysis of TwoInsects · 2025Article
- Role of metabolism, resistance, and/or antagonism as drivers of endomicrobiomes assemblage in Origanum heracleoticum L.Communications biology · 2025Article
- Deciphering the profiles of grapevine microbiomes from rhizosphere-to-leaf compartments using multi-omic analysis.Frontiers in plant science · 2025Article
- Host-specific and environmental core bacteria differentially shape the stability and function of theISME communications · 2025Article
- Dynamic interaction of antibiotic resistance between plant microbiome and organic fertilizers: sources, dissemination, and health risks.World journal of microbiology & biotechnology · 2024Review
- Beyond correlation: Understanding the causal link between microbiome and plant health.Heliyon · 2024Review
- The phyllosphere of Nigerian medicinal plants, Euphorbia lateriflora and Ficus thonningii is inhabited by a specific microbiota.Scientific reports · 2024Article
- Applied microbiology of the phyllosphere.Applied microbiology and biotechnology · 2024Review
- Microbiome Interconnectedness throughout Environments with Major Consequences for Healthy People and a Healthy Planet.Microbiology and molecular biology reviews : MMBR · 2023Review
- [Health risks from crop irrigation with treated wastewater containing antibiotic residues, resistance genes, and resistant microorganisms].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArugula is a traditional medicinal plant and popular leafy green today. It is mainly consumed raw in the Western cuisine and known to contain various bioactive secondary metabolites. However, arugula has been also associated with high-profile outbreaks causing severe food-borne human diseases. A multiphasic approach integrating data from metagenomics, amplicon sequencing, and arugula-derived bacterial cultures was employed to understand the specificity of the indigenous microbiome and resistome of the edible plant parts.
resultsOur results indicate that arugula is colonized by a diverse, plant habitat-specific microbiota. The indigenous phyllosphere bacterial community was shown to be dominated by Enterobacteriaceae, which are well-equipped with various antibiotic resistances. Unexpectedly, the prevalence of specific resistance mechanisms targeting therapeutic antibiotics (fluoroquinolone, chloramphenicol, phenicol, macrolide, aminocoumarin) was only surpassed by efflux pump assignments.
conclusionsEnterobacteria, being core microbiome members of arugula, have a substantial implication in the overall resistome. Detailed insights into the natural occurrence of antibiotic resistances in arugula-associated microorganisms showed that the plant is a hotspot for distinctive defense mechanisms. The specific functioning of microorganisms in this unusual ecosystem provides a unique model to study antibiotic resistances in an ecological context.
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