Evidence map›Paper›PMID 30696456›Full record

ArticleAnnals of clinical microbiology and antimicrobials2019

Antimicrobial stewardship program (ASP): an effective implementing technique for the therapy efficiency of meropenem and vancomycin antibiotics in Iranian pediatric patients.

Aliakbar Rahbarimanesh, Sayed Yousef Mojtahedi, Payman Sadeghi, Maryam Ghodsi, Sara Kianfar, Leila Khedmat, Saeedreza Jamali Moghadam Siyahkali, Mohammad Kaji Yazdi, Anahita Izadi

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Aliakbar RahbarimaneshDepartment of Pediatric Infection Disease, Bahrami Hospital, Tehran University of Medical Science, Shahid Kiaee Street (Ghasem Abad), Damavand Street, 1641744991, Tehran, Iran.
Sayed Yousef MojtahediDepartment of Pediatric Nephrology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Payman SadeghiBahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Maryam GhodsiDepartment of Pediatric, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sara KianfarBahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Leila KhedmatHealth Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Saeedreza Jamali Moghadam SiyahkaliZiaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Kaji YazdiDepartment of Pediatric Hematology and Oncology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Anahita IzadiDepartment of Pediatric Infection Disease, Bahrami Hospital, Tehran University of Medical Science, Shahid Kiaee Street (Ghasem Abad), Damavand Street, 1641744991, Tehran, Iran. dr.anahita.izadi@gmail.com.
Tehran University of Medical Sciences · IRUniversity of Tehran · IRBaqiyatallah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial stewardship program (ASP) is a distinguished method to improve the prescription and efficacy of antibiotics.

aimThe efficacy of ASP and conventional methods was compared to measure the effectiveness of meropenem (MPM) and vancomycin (VMN) antibiotics in pediatric patients.

designIn an interventional quasi-experimental study, 135 children admitted in Children's Hospital affiliated to University of Medical Sciences in time periods of 2014-2015 and 2015-2016 were assessed.

methodsThe conventional and ASP methods in 2014-2015 and 2015-2016 were respectively utilized to provide the best antimicrobial therapy of MPM and VMN antibiotics in patient children. The data of mortality rate (MR), antibiotic prescription (AP), antibiotic dose (ADe), antibiotic duration (ADn), length of hospital stay (LOHS), and blood cultures (BCs) were compared across the years using the Chi square, independent t test, and Fisher's exact test.

resultsThe levels of MR, AP, ADe, ADn, LOHS, and positive BCs using the ASP method in 2015-2016 were significantly lower those of in 2014-2015 using the conventional one (p < 0.05).

conclusionsThe ASP method versus conventional one with a better efficacy can be employed as an antibiotic administration guide for MPM and VMN in the therapy of patients in community-based hospitals.

Indexed as

Antibiotic ProphylaxisAnti-Infective AgentsAntimicrobial StewardshipBlood CultureChi-Square DistributionDrug Administration ScheduleHospitals, PediatricHumansInfantIranLength of StayMeropenemMortalityPrescription DrugsProgram EvaluationTime FactorsAnti-Infective AgentsMeropenemPrescription DrugsVancomycinAntibiotic therapyAntimicrobial managementAntimicrobial resistanceASP interventionMeropenemVancomycin

Identifiers

PMID30696456
PMCPMC6352345
OpenAlexW2915164641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.