Evidence map›Paper›PMID 30696435›Full record

ArticleLipids in health and disease2019

Blood pressure and low-density lipoprotein cholesterol control status in Chinese hypertensive dyslipidemia patients during lipid-lowering therapy.

Xiaowei Yan, Yong Li, Yugang Dong, Yanhua Wu, Jihu Li, Rui Bian, Dayi Hu

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Traditional Chinese Patent Medicine for Primary Hypertension: A Bayesian Network Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Xiaowei YanDepartment of Cardiology, Peking Union Medical College Hospital, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China. yanxiaowei011618@163.com.
Yong LiDepartment of Cardiology, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12, Wulumuqi Rd. (middle), Shanghai, 200040, China.
Yugang DongDepartment of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Second Zhongshan Road, Guangzhou, 510080, China.
Yanhua WuMedical Affairs, Merck Sharp & Dohme (China) Holding Ltd. Building A, Headquarters Park Phase 2, 1582 Gumei Road, Xuhui District, Shanghai, 200233, China.
Jihu LiOutcome Research, Merck Sharp & Dohme (China) Holding Ltd. Building A, Headquarters Park Phase 2, 1582 Gumei Road, Xuhui District, Shanghai, 200233, China.
Rui BianMedical Affairs, Merck Sharp & Dohme (China) Holding Ltd. Building A, Headquarters Park Phase 2, 1582 Gumei Road, Xuhui District, Shanghai, 200233, China.
Dayi HuDepartment of Cardiology, Peking University People's Hospital, No. 11 Xizhimen South Street Xicheng District, Beijing, 100044, China. Hudayi080615@163.com.
Huashan Hospital · CNPeking Union Medical College Hospital · CNPeking University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

Merck & Co., Inc., Kenilworth, NJ USA IISP#39298
6 · The paper itself

Abstract

ᅟ: The present study comprised 17,096 Chinese hypertensive dyslipidemia patients who received lipid-lowering treatment for > 3 months in order to investigate blood pressure (BP) as well as low-density lipoprotein cholesterol (LDL-C) goal attainment rates in Chinese hypertensive dyslipidemia patients on antidyslipidemia drugs. The factors that interfered with BP, or BP and LDL-C goal attainment rates and antihypertensive treatment patterns, were analyzed. In total, 89.9% of the 17,096 hypertensive dyslipidemia patients received antihypertensive medications mainly consisting of a calcium channel blocker (CCB) (48.7%), an angiotensin receptor antagonist (ARB) (25.4%) and an angiotensin-converting enzyme inhibitor (ACEI) (15.1%). In cardiology departments, usage rates of β-blockers (19.2%) were unusually high compared to other departments (4.0-8.3%), whereas thiazide diuretics were prescribed at the lowest rate (0.3% vs 1.2-3.6%). The overall goal attainment rates for combined BP and LDL-C as well as BP or LDL-C targets were 22.9, 31.9 and 60.1%, respectively. The lowest BP, LDL-C and BP combined with LDL-C goal attainment rates were achieved in endocrine departments (19.9, 48.9 and 12.4%, respectively). Combination therapies showed no benefit particularly for BP goal achievement. A multivariate logistic regression analysis showed that age < 65 years, alcohol consumption, diabetes, coronary heart disease (CHD), cerebrovascular disease (CVD), chronic kidney disease (CKD), body mass index (BMI) ≥ 28 kg/m

Indexed as

AgedAlcohol DrinkingAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsBlood PressureBody Mass IndexCalcium Channel BlockersCholesterol, LDLCoronary DiseaseDyslipidemiasFemaleHumansHypertensionLipidsMaleAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsCalcium Channel BlockersCholesterol, LDLLipidsSodium Chloride Symporter InhibitorsBlood pressure statusDYSISDyslipidemiaHypertensionLow-density lipoprotein cholesterol

Identifiers

PMID30696435
PMCPMC6352342
OpenAlexW2919192762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.