Evidence map›Paper›PMID 30696387›Full record

Trial reportJournal of neurotrauma2019

Exercise-Induced Alterations in Sympathetic-Somatomotor Coupling in Incomplete Spinal Cord Injury.

Tanya Onushko, Gordhan B Mahtani, Gabrielle Brazg, T George Hornby, Brian D Schmit

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tanya OnushkoDepartment of Biomedical Engineering, Marquette University, Milwaukee, Wisconsin.
Gordhan B MahtaniDepartment of Orthopaedic Surgery, Stanford University, Stanford, California.
Gabrielle BrazgShirley Ryan AbilityLab, Chicago, Illinois.
T George HornbyDepartment of Physical Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis, Indiana.
Brian D SchmitDepartment of Biomedical Engineering, Marquette University, Milwaukee, Wisconsin.

Funding

Sympathetic-somatomotor coupling in human SCIR01NS079751 · NINDS · MARQUETTE UNIVERSITY · PI HORNBY, THOMAS GEORGE, SCHMIT, BRIAN D · 2013 to 2017
$1.6M
NINDS NIH HHS R01 NS079751
6 · The paper itself

Abstract

The aim of this study was to understand how high- and low-intensity locomotor training (LT) affects sympathetic-somatomotor (SS) coupling in people with incomplete spinal cord injury (SCI). Proper coupling between sympathetic and somatomotor systems allows controlled regulation of cardiovascular responses to exercise. In people with SCI, altered connectivity between descending pathways and spinal segments impairs sympathetic and somatomotor coordination, which may have deleterious effects during exercise and limit rehabilitation outcomes. We postulated that high-intensity LT, which repeatedly engages SS systems, would alter SS coupling. Thirteen individuals (50 ± 7.2 years) with motor incomplete spinal cord injuries (American Spinal Injury Association Impairment Scale C or D; injury level >T6) participated in a locomotor treadmill training program. Patients were randomized into either a high-intensity (high-LT; 70-85% of maximum predicted heart rate;

Indexed as

Physical Therapy ModalitiesAdultBlood PressureFemaleHeart RateHumansMaleMiddle AgedMuscle StrengthReflex, StretchSpinal Cord InjuriesSympathetic Nervous SystemTreatment Outcomelocomotor trainingrehabilitationspinal cord injurysympathetic nervous system

Identifiers

PMID30696387
PMCPMC6727466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.