Evidence map›Paper›PMID 30696053›Full record

ArticleInternational journal of molecular sciences2019

Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

Dominika Deborska-Materkowska, Agnieszka Perkowska-Ptasinska, Anna Sadowska-Jakubowicz, Jolanta Gozdowska, Michał Ciszek, Joanna Pazik, Agata Ostaszewska, Maciej Kosieradzki, Jacek Nowak, Magdalena Durlik

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. The Role of Killer Ig-like Receptors in Diseases from A to Z.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. TheFrontiers in immunology · 2023
    Article
  7. Review
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dominika Deborska-MaterkowskaDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. dominika.deborska-materkowska@wum.edu.pl.
Agnieszka Perkowska-PtasinskaDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. agnieszka.perkowska-ptasinska@wum.edu.pl.
Anna Sadowska-JakubowiczDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. andziaa@wp.pl.
Jolanta GozdowskaDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. jola-md@prokonto.pl.
Michał CiszekDepartment of Immunology, Transplantology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. mciszek@onet.pl.
Joanna PazikDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. jpazik@poczta.fm.ORCID 0000-0001-9757-4382
Agata OstaszewskaDepartment of General and Transplant Surgery, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. ag.ostaszewska@gmail.com.
Maciej KosieradzkiDepartment of General and Transplant Surgery, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. mpkosieradzki@gmail.com.
Jacek NowakDepartment of Immunogenetics Institute of Hematology and Transfusion Medicine 14 Indira Gandhi Street, 02-776 Warsaw, Poland. jnowak@ihit.waw.pl.ORCID 0000-0002-3474-7597
Magdalena DurlikDepartment of Transplantation Medicine, Nephrology, Internal Diseases, T. Orłowski Institute of Transplantation Medical University of Warsaw, 59 Nowogrodzka Street, 02-006 Warsaw, Poland. magdalena.durlik@wum.edu.pl.
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with cytomegalovirus (CMV) remains a major problem in kidney transplant recipients, resulting in serious infectious complications and occasionally mortality. Accumulating evidence indicates that natural killer cell immunoglobulin-like receptors (KIRs) and their ligands affect the susceptibility to various diseases, including viral infections (e.g., CMV infection). We investigated whether KIR genes and their ligands affect the occurrence of CMV infection in a group of 138 kidney transplant recipients who were observed for 720 days posttransplantation. We typed the recipients for the presence of KIR genes (human leukocyte antigen C1 [HLA-C1], HLA-C2, HLA-A, HLA-B, and HLA-DR1) by polymerase chain reaction with sequence-specific primers. The multivariate analysis revealed that the lack of

Indexed as

Kidney TransplantationAdultAgedCytomegalovirus InfectionsFemaleGene FrequencyGenetic MarkersGenotypeHaplotypesHLA-C AntigensHumansKaplan-Meier EstimateMaleMiddle AgedReceptors, KIRRisk FactorsGenetic MarkersHLA-C AntigensReceptors, KIRcytomegalovirushuman leukocyte antigenkidney transplantationkiller-cell immunoglobulin-like receptorlymphocytopenianatural killer cell

Identifiers

PMID30696053
PMCPMC6387393
OpenAlexW2912012688

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.