Evidence map›Paper›PMID 30695995›Full record

ReviewInternational journal of molecular sciences2019

The Effects of Resveratrol in the Treatment of Metabolic Syndrome.

Chih-Yao Hou, You-Lin Tain, Hong-Ren Yu, Li-Tung Huang

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07395921 (Effects of Resveratrol Supplementation on Inflammatory Biomarkers and Cardiometabolic Parameters in Community-dwelling Adults.), which is not on this map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07395921 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Resveratrol Supplementation on Inflammatory Biomarkers and Cardiometabolic Parameters in Community-dwelling Adults. (RESINCA-trial)

TypeinterventionalSponsorCenter for Research and Innovation Viña Concha y ToroRan2026 to 2026Enrolled75ConditionsInflammation Biomarkers, Cardiometabolic Health Indicators, Antioxidant Status, Inflammation, Antioxidant CapabilitiesArmsRES 120, RES 250, RES 500
3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

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  20. Pennogenin 3-International journal of molecular sciences · 2024
    Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chih-Yao HouDepartment of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung 811, Taiwan. chihyaohou@gmail.com.ORCID 0000-0002-8007-6077
You-Lin TainInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan. tainyl@hotmail.com.ORCID 0000-0002-7059-6407
Hong-Ren YuInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan. yuu2004taiwan@yahoo.com.tw.ORCID 0000-0003-1242-8760
Li-Tung HuangInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan. litung.huang@gmail.com.ORCID 0000-0001-7403-288X
Chang Gung University · TWNational Kaohsiung Marine University · TW

Funding

Chang Gung Memorial Hospital CMRPG8G0632
6 · The paper itself

Abstract

Resveratrol, also known as 3,5,4'-trihydroxystilbene, is a natural polyphenol that occurs as a phytoalexin. It is produced by plant sources such as grapes, apples, blueberries, plums, peanuts, and other oilseeds. This compound has a variety of effects on human health and diseases. This review summarizes the mounting evidence that resveratrol is helpful in treating metabolic syndrome and related disorders. Resveratrol can be provided either early as a reprogramming agent or later as part of treatment. A few of the main mechanisms underlying the beneficial effects of resveratrol on metabolic syndrome are outlined. This review also discusses the potential of resveratrol derivatives as a complementary or alternative medicine. In conclusion, resveratrol could be a useful regimen for the prevention and treatment of metabolic syndrome and its related conditions.

Indexed as

AnimalsDisease Models, AnimalHumansMetabolic SyndromeResveratrolResveratrolhigh-fat dietmetabolic syndromeresveratrolresveratrol derivatives

Identifiers

PMID30695995
PMCPMC6387422
OpenAlexW2911285956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.