Evidence map›Paper›PMID 30694516›Full record

ArticleJournal of autism and developmental disorders2019

Brief Report: Evaluation of the Short Quantitative Checklist for Autism in Toddlers (Q-CHAT-10) as a Brief Screen for Autism Spectrum Disorder in a High-Risk Sibling Cohort.

Sarah Raza, Lonnie Zwaigenbaum, Lori-Ann R Sacrey, Susan Bryson, Jessica Brian, Isabel M Smith, Kyle Reid, Wendy Roberts, Peter Szatmari, Tracy Vaillancourt and 2 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Diagnosis and Assessment of Autism Spectrum Disorder in South Korea.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Autism spectrum disorder.Nature reviews. Disease primers · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Sarah RazaDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada. sraza@ualberta.ca.ORCID http://orcid.org/0000-0002-3666-8585
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Lori-Ann R SacreyDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Susan BrysonIWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Jessica BrianBloorview Research Institute, Toronto, ON, Canada.
Isabel M SmithIWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Kyle ReidAutism Research Centre (E209), Glenrose Rehabilitation Hospital, 10230-111 Avenue, Edmonton, AB, T5G 0B7, Canada.
Wendy RobertsISAND, Toronto, ON, Canada.
Peter SzatmariUniversity of Toronto, Toronto, ON, Canada.
Tracy VaillancourtUniversity of Ottawa, Ottawa, ON, Canada.
Caroline RoncadinMcMaster Children's Hospital-Hamilton Health Sciences, Hamilton, ON, Canada.
Nancy GaronMount Allison University, Sackville, NB, Canada.
University of Alberta · CADalhousie University · CACentre for Addiction and Mental Health · CAGlenrose Rehabilitation Hospital · CAMcMaster Children's Hospital · CAMount Allison University · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the potential of the short form of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10) to identify autism spectrum disorder (ASD) in a high-risk sibling cohort. High-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers were assessed prospectively at 18 and 24 months of age using the Q-CHAT-10 and underwent blind diagnostic assessment for ASD at 36 months of age. The results indicated that at 18 and 24 months, total score differentiated between HR toddlers subsequently diagnosed with ASD from other HR and LR toddlers. The sensitivity at both time points was acceptable; however, the specificity was below the level recommended for clinical application.

Indexed as

SiblingsAutism Spectrum DisorderChecklistChild BehaviorChild, PreschoolFemaleGenetic Predisposition to DiseaseHumansInfantMaleMass ScreeningSurveys and QuestionnairesAutismAutism spectrum disorderBehavioral signsClassification accuracyEarly screeningInfant siblings

Identifiers

PMID30694516
OpenAlexW2912406012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.