Evidence map›Paper›PMID 30694513›Full record

ReviewOphthalmology and therapy2019

Ocular Mucous Membrane Pemphigoid: Current State of Pathophysiology, Diagnostics and Treatment.

Panagiotis Georgoudis, Francesco Sabatino, Nora Szentmary, Sotiria Palioura, Eszter Fodor, Samer Hamada, Hendrik P N Scholl, Zisis Gatzioufas

Open access · goldAbstract readReview
In one paragraph

Review in Ophthalmology and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Challenges and advances in ocular mucous membrane pemphigoid (OMMP); from pathogenesis to treatment strategies.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  9. Article
  10. Ocular surface glycocalyx in health and disease.Frontiers in cell and developmental biology · 2025
    Review
  11. Impact of Exposomes on Ocular Surface Diseases.International journal of molecular sciences · 2023
    Review
  12. Application of biomaterials and nanotechnology in corneal tissue engineering.The Journal of international medical research · 2023
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Tofacitinib for refractory ocular mucous membrane pemphigoid.American journal of ophthalmology case reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 5 countries.

Panagiotis GeorgoudisWhipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Francesco SabatinoMoorfields Eye Hospital, London, UK.
Nora SzentmaryDepartment of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany.
Sotiria PaliouraAthens Vision Eye Institute, Athens, Greece.
Eszter FodorDepartment of Ophthalmology, Semmelweis University, Budapest, Hungary.
Samer HamadaCorneo-Plastic Unit, Queen Victoria Hospital, East Grinstead, UK.
Hendrik P N SchollDepartment of Ophthalmology, Basel University Hospital, Basel, Switzerland.
Zisis GatzioufasDepartment of Ophthalmology, Basel University Hospital, Basel, Switzerland. zisisg@hotmail.com.
Athens Eye Hospital · GRInstitute of Molecular and Clinical Ophthalmology Basel · CHMoorfields Eye Hospital · GBQueen Victoria Hospital · GBSaarland University · DESemmelweis University · HUUniversity Hospital of Basel · CHWhipps Cross University Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mucous membrane pemphigoid (MMP) is a systemic cicatrizing autoimmune disease that primarily affects orificial mucous membranes, such as the conjunctiva, the nasal cavity, the oropharynx, and the genitalia. Ocular involvement occurs in about 70% of all MMP cases. Ocular MMP (OcMMP) also encompasses the conditions linear immunoglobulin A disease, mucosal dominated epidermolysis bullosa acquisita, and anti-laminin 332/anti-epiligrin/anti-laminin 5 pemphigoid. It is a complex clinical entity that may lead to ocular surface failure and result in inflammatory and infectious complications, as well as potentially devastating visual loss. Early diagnosis and appropriate treatment are of paramount importance and require a high level of expertise as this condition can be extremely challenging to diagnose and treat even for experienced clinicians. In this review we provide an up-to-date insight on the pathophysiology of OcMMP, with an emphasis on the current state of its diagnostics and therapeutics. Our the aim is to increase our understanding of OcMMP and highlight modern diagnostic and therapeutic options.

Indexed as

DiagnosticsMucousOcular pemphigoidPathophysiologyTreatment

Identifiers

PMID30694513
PMCPMC6393250
OpenAlexW2913710132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.