ArticleDysphagia2019
Relationship Between Laryngeal Sensation, Length of Intubation, and Aspiration in Patients with Acute Respiratory Failure.
Article in Dysphagia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05108896 (Aspiration in Acute Respiratory Failure Survivors), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aspiration in Acute Respiratory Failure Survivors
Who cites it
21 citing papers in PubMed, 61 citations in OpenAlex.
- Effects of expiratory muscle strength training on swallowing in survivors of critical illness: A systematic review and narrative synthesis.Journal of the Intensive Care Society · 2026Article
- Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia.Nutrients · 2026Article
- [Postextubation dysphagia : Challenges regarding interdisciplinary collaboration in intensive care units].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Article
- Research report: Management of dysphagia using pharyngeal electrical stimulation in the general intensive care population - A service development.Journal of the Intensive Care Society · 2024Article
- Bedside diagnosis of silent aspiration using mobile dynamic digital radiography: a preliminary study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Dysphagia Prevalence and Outcomes Associated with the Evolution of COVID-19 and Its Variants in Critically Ill Patients.Dysphagia · 2024Observational
- Instrument adaptation and preliminary validation study of the Laryngeal Hypersensitivity Questionnaire used for assessment of laryngeal symptoms in patients with artificial airways.Australian critical care : official journal of the Confederation of Australian Critical Care Nurses · 2024Article
- Post-extubation Assessment of Laryngeal Symptoms and Severity (PALSS) in the Intensive Care Unit: Protocol of a Prospective Cohort Study.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2024Article
- Postorotracheal intubation dysphagia in patients with COVID-19: A retrospective study.Sao Paulo medical journal = Revista paulista de medicina · 2024Article
- Characteristics of post-stroke dysphagia: A retrospective study based on FEES.Brain and behavior · 2023Article
- Clinical profile and recovery pattern of dysphagia in the COVID-19 patient: A prospective observational cohort within NSW.Australian critical care : official journal of the Confederation of Australian Critical Care Nurses · 2023Observational
- Successful Treatment of Post COVID-19 Neurogenic Dysphagia with Botulinum Toxin.European journal of case reports in internal medicine · 2023Article
- [Postextubation dysphagia in intensive care patients : Current findings and clinical recommendations].Die Anaesthesiologie · 2022Review
- Dysphagia Characteristics of Patients Post SARS-CoV-2 During Inpatient Rehabilitation.Archives of physical medicine and rehabilitation · 2022Article
- Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure.Dysphagia · 2021Article
- Correction to: Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure.Dysphagia · 2021Article
- Effects of percutaneous injection laryngoplasty on voice and swallowing problems in cancer-related unilateral vocal cord paralysis.Laryngoscope investigative otolaryngology · 2021Article
- Targeting the sensory feedback within the swallowing network-Reversing artificially induced pharyngolaryngeal hypesthesia by central and peripheral stimulation strategies.Human brain mapping · 2021Article
- Aspiration and severe exacerbations in COPD: a prospective study.ERJ open research · 2021Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 1 country.
Funding
Abstract
Dysphagia is common in hospitalized patients post-extubation and associated with poor outcomes. Laryngeal sensation is critical for airway protection and safe swallowing. However, current understanding of the relationship between laryngeal sensation and aspiration in post-extubation populations is limited. Acute respiratory failure patients requiring intensive care unit admission and mechanical ventilation received a Flexible Endoscopic Evaluation of Swallowing (FEES) within 72 h of extubation. Univariate and multivariable analyses were performed to examine the relationship between laryngeal sensation, length of intubation, and aspiration. Secondary outcomes included pharyngolaryngeal secretions, pneumonia, and diet recommendations. One-hundred and three patients met inclusion criteria. Fifty-one patients demonstrated an absent laryngeal adductor reflex (LAR). Altered laryngeal sensation correlated with the presence of secretions (p = 0.004). There was a significant interaction between the LAR, aspiration, and duration of mechanical ventilation. Altered laryngeal sensation was significantly associated with aspiration on FEES only in patients with a shorter length of intubation (p = 0.008). Patients with altered laryngeal sensation were prescribed significantly more restricted liquid (p = 0.03) and solid (p = 0.001) diets. No relationship was found between laryngeal sensation and pneumonia. There is a high prevalence of laryngeal sensory deficits in mechanically ventilated patients post-extubation. Altered laryngeal sensation was associated with secretions, aspiration, and modified diet recommendations especially in those patients with a shorter length of mechanical ventilation. These results demonstrate that laryngeal sensory abnormalities impact the development of post-extubation dysphagia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.