Evidence map›Paper›PMID 30694180›Full record

ArticleeLife2019

Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci.

Sonia Q Sen, Sachin Chanchani, Tony D Southall, Chris Q Doe

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Hox Gene,Molecular biology of the cell · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. The Hox Gene,bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Temporal regulation of neural diversity in Drosophila and vertebrates.Seminars in cell & developmental biology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sonia Q SenInstitute of Neuroscience, Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID 0000-0003-4693-3378
Sachin ChanchaniInstitute of Neuroscience, Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.
Tony D SouthallDepartment of Life Sciences, Imperial College London, London, United Kingdom.ORCID 0000-0002-8645-4198
Chris Q DoeInstitute of Neuroscience, Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID 0000-0001-5980-8029
Howard Hughes Medical Institute · USImperial College London · GB

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
GENETIC AND MOLECULAR STUDIES OF NEUROGENESISR01HD027056 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe · 1989 to 2026
$5.0M
Genetic and Molecular Studies of NeurogenesisR37HD027056 · NICHD · UNIVERSITY OF OREGON · PI DOE, CHRIS Q · 2012 to 2021
$3.0M
NICHD NIH HHS R01 HD027056NICHD NIH HHS R37 HD027056NIH HHS HD27056NIH HHS P40 OD018537
6 · The paper itself

Abstract

Spatial and temporal cues are required to specify neuronal diversity, but how these cues are integrated in neural progenitors remains unknown.

Indexed as

AnimalsBrainCell DifferentiationCell LineageCell ProliferationChromatinDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalHumansModels, BiologicalNeural Stem CellsNeuronsNuclear ProteinsPAX3 Transcription FactorChromatinDNA-Binding ProteinsDrosophila Proteinsgsb protein, Drosophilahb protein, DrosophilaNuclear ProteinsPAX3 Transcription FactorTrans-ActivatorsTranscription FactorschromatinDamIDdevelopmental biologyD. melanogasterneuroblastneurosciencespatial patterningstem celltemporal identity

Identifiers

PMID30694180
PMCPMC6377230
OpenAlexW2912341255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.