ArticleeLife2019
TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization.
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Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
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Who cites it
35 citing papers in PubMed, 54 citations in OpenAlex.
- Stochastic growth and ligand-receptor interaction-mediated stabilization generate stereotyped dendritic arbors.Nature neuroscience · 2026Article
- Retinal ribbon synapses and the potential functional role of TIAM1: A structural and molecular perspective.Molecular vision · 2026Review
- A dendritic guidance receptor functions in both ligand dependent and independent modes.PLoS genetics · 2025Article
- P-Rex1 limits the agonist-induced internalization of GPCRs independently of its Rac-GEF activity.Cell reports · 2025Article
- The kinetochore protein KNL-1 regulates the actin cytoskeleton to control dendrite branching.The Journal of cell biology · 2025Article
- P-Rex1 controls phagocytosis and the killing of bacteria by murine neutrophils independently of its catalytic activity.Frontiers in immunology · 2025Article
- Endocytosis restricts dendrite branching via removing ectopically localized branching ligands.Nature communications · 2024Article
- RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.Genetics · 2024Article
- Dendrite morphogenesis in Caenorhabditis elegans.Genetics · 2024Review
- Structural changes of CA1 pyramidal neurons after stroke in the contralesional hippocampus.Brain pathology (Zurich, Switzerland) · 2024Article
- Article
- TIAM-1 regulates polarized protrusions during dorsal intercalation in the Caenorhabditis elegans embryo through both its GEF and N-terminal domains.Journal of cell science · 2024Article
- Optimization of RNAi efficiency in PVD neuron of C. elegans.PloS one · 2024Article
- Convertase-dependent regulation of membrane-tethered and secreted ligands tunes dendrite adhesion.Development (Cambridge, England) · 2023Article
- Article
- Microanatomical study of pyramidal neurons in the contralesional somatosensory cortex after experimental ischemic stroke.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Two intrinsic timing mechanisms set start and end times for dendritic arborization of a nociceptive neuron.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- TIAM-1 differentially regulates dendritic and axonal microtubule organization in patterning neuronal development through its multiple domains.PLoS genetics · 2022Article
- The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons.PLoS genetics · 2022Article
- Specific N-glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning.EMBO reports · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Leo Th Tang *Department of Genetics, Albert Einstein College of Medicine, Bronx, United States.
Carlos A Diaz-Balzac *Department of Genetics, Albert Einstein College of Medicine, Bronx, United States.ORCID 0000-0002-4723-1282
Maisha RahmanDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, United States.
Nelson J Ramirez-SuarezDepartment of Genetics, Albert Einstein College of Medicine, Bronx, United States.ORCID 0000-0001-7394-860X
Yehuda SalzbergDepartment of Genetics, Albert Einstein College of Medicine, Bronx, United States.
Maria I Lázaro-PeñaDepartment of Genetics, Albert Einstein College of Medicine, Bronx, United States.
Hannes E BülowDepartment of Genetics, Albert Einstein College of Medicine, Bronx, United States.ORCID 0000-0002-6271-0572
Albert Einstein College of Medicine · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6MTRAINING PROGRAM IN CELLULAR &MOLEC. BIOLOGY &GENETICST32GM007491 · NIGMS · YESHIVA UNIVERSITY · PI QUERY, CHARLES C · 1985 to 2021
$17.0MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5MSupport for the Rose F. Kennedy IDDRCU54HD090260 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GREALLY, JOHN · 2016 to 2020
$6.0MTranslational Neuroimaging CoreP30HD071593 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WALKLEY, STEVEN UPSHAW · 2011 to 2015
$5.6MGenetic Analyses of Dendrite Development in Caenorhabditis elegansR01NS096672 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BUELOW, HANNES ERICH · 2016 to 2020
$1.8MEstablishing the Role of a Novel Conserved Gene in Dendrite MorphogenesisR21NS081505 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BUELOW, HANNES ERICH · 2013 to 2014
$457kIdentification of Novel Loci Interacting with the Kallmann Syndrome Gene Kal-1F31HD066967 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DIAZ-BALZAC, CARLOS ANTONIO · 2010 to 2013
$168kUncovering the role of leukocyte cell-derived chemotaxin 2 (lect-2) in dendrite morphogenesisF31NS100370 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI RAHMAN, MAISHA · 2017 to 2019
$137kEunice Kennedy Shriver National Institute of Child Health and Human Development F31HD066967NICHD NIH HHS F31 HD066967NICHD NIH HHS P30 HD071593NICHD NIH HHS U54 HD090260NIGMS NIH HHS T32 GM007288NIGMS NIH HHS T32GM007288NIGMS NIH HHS T32 GM007491NIGMS NIH HHS T32GM07491NIH HHS P40 OD010440NINDS NIH HHS F31 NS100370NINDS NIH HHS F31NS100370NINDS NIH HHS R01 NS096672NINDS NIH HHS R01NS096672NINDS NIH HHS R21NS081505
Abstract
Dendritic arbors are crucial for nervous system assembly, but the intracellular mechanisms that govern their assembly remain incompletely understood. Here, we show that the dendrites of PVD neurons in
Indexed as
ActinsAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsClaudinsGene Expression RegulationMembrane ProteinsNervous SystemNeurogenesisNeuronal PlasticityNeuronsPDZ DomainsProtein BindingProtein Transportrac1 GTP-Binding ProteinSynaptic TransmissionActinsCaenorhabditis elegans ProteinsClaudinsDMA-1 protein, C eleganshpo-30 protein, C elegansMembrane Proteinsrac1 GTP-Binding ProteinTIAM-1 protein, C elegansT-Lymphoma Invasion and Metastasis-inducing Protein 1actinC. elegansclaudindendritesdevelopmental biologyGEF independentguanine nucleotide exchange factorneurosciencePVD
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.