Evidence map›Paper›PMID 30693827›Full record

ArticleJournal of neurotrauma2019

Impaired Cerebral Vasoreactivity Despite Symptom Resolution in Sports-Related Concussion.

Sushmita Purkayastha, Farzaneh A Sorond, Sydney Lyng, Justin Frantz, Megan N Murphy, Linda S Hynan, Tonia Sabo, Kathleen R Bell

Abstract read
In one paragraph

Article in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Preseason Cerebrovascular Function in Adolescent Athletes.Annals of biomedical engineering · 2021
    Article
  5. Article
  6. Article
  7. Pediatric Sports-Related Concussion: An Approach to Care.American journal of lifestyle medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sushmita Purkayastha1Department of Applied Physiology and Wellness, Simmons School of Education and Human Development, Southern Methodist University, Dallas, Texas.
Farzaneh A Sorond3Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Sydney Lyng1Department of Applied Physiology and Wellness, Simmons School of Education and Human Development, Southern Methodist University, Dallas, Texas.
Justin Frantz1Department of Applied Physiology and Wellness, Simmons School of Education and Human Development, Southern Methodist University, Dallas, Texas.
Megan N Murphy1Department of Applied Physiology and Wellness, Simmons School of Education and Human Development, Southern Methodist University, Dallas, Texas.
Linda S Hynan4Department of Clinical Science and Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas.
Tonia Sabo5Department of Pediatrics/Division of Pediatric Neurology & Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas.
Kathleen R Bell2Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, Dallas, Texas.

Funding

Cerebral Small Vessels in Motor and Cognitive Decline: Neuroimaging Signatures of Vulnerability & ResilienceR01NS085002 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FARZANEH A SOROND · 2014 to 2026
$3.8M
NINDS NIH HHS R01 NS085002
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is associated with increased risk of later-life neurodegeneration and dementia. However, the underpinning mechanisms are poorly understood, and secondary injury resulting from perturbed physiological processes plays a significant role. Cerebral vasoreactivity (CVR), a measure of hemodynamic reserve, is known to be impaired in TBI. However, the temporal course of this physiological perturbation is not established. We examined CVR and clinical symptoms on day 3 (T1), day 21 (T2), and day 90 (T3) after concussion in collegiate athletes and cross-sectionally in non-injured controls. Changes in middle cerebral artery blood flow velocity (MCAV; transcranial Doppler ultrasonography) were measured during changes in end-tidal CO

Indexed as

AthletesAthletic InjuriesBlood Flow VelocityBrain ConcussionCerebrovascular CirculationFemaleHemodynamicsHumansMaleUltrasonography, Doppler, TranscranialYoung Adultcerebral blood flowcerebral reactivityheadachereturn-to-playtraumatic brain injury

Identifiers

PMID30693827
PMCPMC6909747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.