Evidence map›Paper›PMID 30692806›Full record

ArticleAsian journal of transfusion science

Therapeutic plasma exchange as a life-saving therapy in a suspected case of autoimmune encephalitis: A case report from a tertiary health-care center.

Prashant Kumar Pandey, Nitin Agarwal, Manish Gupta

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Multimodal temporal dissociation in anti-GABAFrontiers in immunology · 2026
    Article
  2. Article
  3. Therapeutic Plasma Exchange: An Indispensable Therapy for Severe Neurological Condition.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prashant Kumar PandeyDepartment of Transfusion Medicine, Jaypee Hospital, Noida, Uttar Pradesh, India.
Nitin AgarwalDepartment of Transfusion Medicine, Jaypee Hospital, Noida, Uttar Pradesh, India.
Manish GuptaDepartment of Neurology, Jaypee Hospital, Noida, Uttar Pradesh, India.
Jaypee Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In half of the suspected autoimmune encephalitis (AIE) patients, no antibodies are identified despite extensive investigation. Therapeutic plasma exchange (TPE) is a potential first-line therapy for various subtypes of AIE. Here, we present a case of autoantibody-negative-suspected AIE, managed successfully with TPE after patient showed no response to steroids. A total of 5 sessions of TPE was done. One standard TPE procedure session was 1.2-1.5 plasma volume exchanges using 5% albumin as a replacement fluid. After five sessions, patient's clinical condition improved significantly, and a repeated magnetic resonance imaging after 5th cycle of TPE revealed a reduction in the areas of signal alteration. This was suggestive of regression of disease. Patient was discharged on 10th day of hospital admission. With early suspicion even in the absence of detectable autoantibodies, TPE plays an important role in the management of encephalitis.

Indexed as

Autoimmune encephalitiscorticosteroidintravenous immunoglobulinstherapeutic plasma exchange

Identifiers

PMID30692806
PMCPMC6327764
OpenAlexW2904315126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.