ArticleNature plants2019
Introducing curcumin biosynthesis in Arabidopsis enhances lignocellulosic biomass processing.
Article in Nature plants, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 68 citations in OpenAlex.
- The Plant Cell Wall: From Structural Diversity and Biosynthesis to Integrity Signaling and Physiological Functions.Plants (Basel, Switzerland) · 2026Review
- Simultaneous Overexpression of FERULOYL-CoA 6'-HYDROXYLASE 1 and COUMARIN SYNTHASE Leads to Coumarin-Enriched Lignin and Improved Saccharification in Greenhouse- and Field-Grown Poplar.Plant biotechnology journal · 2026Article
- A biosynthetic gene cluster for three post-chorismate pathways in Arabidopsis.Nature plants · 2026Article
- Loss-of-function mutation of two phenylpropanoid pathway genes PAL1 and PAL2, coupled with MYB46 upregulation, increases fermentable sugar yield and ethanol production.Journal of biological engineering · 2025Article
- Physiological roles of lignins - tuning cell wall hygroscopy and biomechanics.The New phytologist · 2025Review
- Nature's laboratory: plant metabolic engineering methods using phenylpropanoids as a case study.Biotechnology for biofuels and bioproducts · 2025Review
- Effects ofFrontiers in plant science · 2025Article
- Synthetic-biology approach for plant lignocellulose engineering.Plant biotechnology (Tokyo, Japan) · 2024Article
- Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1.Biotechnology for biofuels and bioproducts · 2024Article
- The plant cell wall-dynamic, strong, and adaptable-is a natural shapeshifter.The Plant cell · 2024Review
- Diarylheptanoid Derivatives (Musellins A-F) and Dimeric Phenylphenalenones from Seed Coats ofJournal of natural products · 2023Article
- High value valorization of lignin as environmental benign antimicrobial.Materials today. Bio · 2023Review
- The impact of curcumin on livestock and poultry animal's performance and management of insect pests.Frontiers in veterinary science · 2023Review
- Editorial: The plant cell wall: advances and current perspectives.Frontiers in plant science · 2023Article
- Lignin engineering in forest trees: From gene discovery to field trials.Plant communications · 2022Review
- Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing.Science advances · 2022Article
- pHBMT1, a BAHD-family monolignol acyltransferase, mediates lignin acylation in poplar.Plant physiology · 2022Article
- Engineering Curcumin Biosynthesis in Poplar Affects Lignification and Biomass Yield.Frontiers in plant science · 2022Article
- Selecting Endophytes for Rhizome Production, Curcumin Content, Biocontrol Potential, and Antioxidant Activities of Turmeric (Curcuma longa).BioMed research international · 2022Article
- Tailoring renewable materials via plant biotechnology.Biotechnology for biofuels · 2021Review
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignin is the main cause of lignocellulosic biomass recalcitrance to industrial enzymatic hydrolysis. By partially replacing the traditional lignin monomers by alternative ones, lignin extractability can be enhanced. To design a lignin that is easier to degrade under alkaline conditions, curcumin (diferuloylmethane) was produced in the model plant Arabidopsis thaliana via simultaneous expression of the turmeric (Curcuma longa) genes DIKETIDE-CoA SYNTHASE (DCS) and CURCUMIN SYNTHASE 2 (CURS2). The transgenic plants produced a plethora of curcumin- and phenylpentanoid-derived compounds with no negative impact on growth. Catalytic hydrogenolysis gave evidence that both curcumin and phenylpentanoids were incorporated into the lignifying cell wall, thereby significantly increasing saccharification efficiency after alkaline pretreatment of the transgenic lines by 14-24% as compared with the wild type. These results demonstrate that non-native monomers can be synthesized and incorporated into the lignin polymer in plants to enhance their biomass processing efficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.