Evidence map›Paper›PMID 30692667›Full record

ArticleNature microbiology2019

Influenza virus uses transportin 1 for vRNP debundling during cell entry.

Yasuyuki Miyake, Jeremy J Keusch, Laure Decamps, Hung Ho-Xuan, Sho Iketani, Heinz Gut, Ulrike Kutay, Ari Helenius, Yohei Yamauchi

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
  9. Article
  10. Enhanced visualization of influenza A virus entry into living cells using virus-view atomic force microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Yasuyuki MiyakeSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.
Jeremy J KeuschFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Laure Decamps *Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Hung Ho-Xuan *Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Sho IketaniSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.
Heinz GutFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Ulrike KutayInstitute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Ari HeleniusInstitute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Yohei YamauchiSchool of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK. yohei.yamauchi@bristol.ac.uk.ORCID http://orcid.org/0000-0002-8233-9133
ETH Zurich · CHUniversity of Bristol · GBFriedrich Miescher Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus is a pathogen of great medical impact. To develop novel antiviral strategies, it is essential to understand the molecular aspects of virus-host cell interactions in detail. During entry, the viral ribonucleoproteins (vRNPs) that carry the RNA genome must be released from the incoming particle before they can enter the nucleus for replication. The uncoating process is facilitated by histone deacetylase 6 (ref.

Indexed as

Virus Internalizationbeta KaryopherinsCell NucleusHumansInfluenza A virusInfluenza, HumanRibonucleoproteinsViral Matrix ProteinsViral ProteinsVirus Replicationbeta KaryopherinsM1 protein, Influenza A virusRibonucleoproteinsTNPO1 protein, humanViral Matrix ProteinsViral Proteins

Identifiers

PMID30692667
OpenAlexW2913096661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.